(Q33928500)

English

Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

amyotrophic lateral sclerosis

0 references

author name string

Soumya S Ray

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Richard J Nowak

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Peter T Lansbury

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Robert H Brown

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

28 February 2005

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

102

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

3639-3644

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

A possible therapeutic target for Lou Gehrig's disease

1 reference

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5 July 2018

Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

1 reference

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5 July 2018

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Evaluation of docking performance: comparative data on docking algorithms

1 reference

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5 July 2018

Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Trans-suppression of misfolding in an amyloid disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Internal packing of helical membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Synthesis and evaluation of inhibitors of transthyretin amyloid formation based on the non-steroidal anti-inflammatory drug, flufenamic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Software for handling macromolecular envelopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Inhibiting transthyretin amyloid fibril formation via protein stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Hydrophobic packing in T4 lysozyme probed by cavity-filling mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

A test of the linear extrapolation of unfolding free energy changes over an extended denaturant concentration range

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553303

5 July 2018

Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

Domain-domain interface packing at conserved Trp-20 in class alpha glutathione transferase impacts on protein stability.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408277102

21 January 2018

FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15738401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovering transthyretin amyloid fibril inhibitors by limited screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/15738401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and evaluation of anthranilic acid-based transthyretin amyloid fibril inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15738401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status

1 reference

https://pubmed.ncbi.nlm.nih.gov/15738401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cu/Zn superoxide dismutase can form pore-like structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/15738401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0408277102

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2005PNAS..102.3639R

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

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