(Q33928530)

30 July 2017

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title

New windows on the mechanism of action of K(ATP) channel openers (English)

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30 July 2017

F M Ashcroft

1

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30 July 2017

F M Gribble

series ordinal

2

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30 July 2017

publication date

1 November 2000

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Trends in Pharmacological Sciences

30 July 2017

published in

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30 July 2017

volume

21

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30 July 2017

issue

11

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30 July 2017

page(s)

439-445

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ATP-regulated K+ channels in cardiac muscle

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

ATP-Sensitive potassium channels: a review of their cardioprotective pharmacology

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Association and stoichiometry of K(ATP) channel subunits

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Octameric stoichiometry of the KATP channel complex

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons

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https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATP

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Sulfonylurea receptors set the maximal open probability, ATP sensitivity and plasma membrane density of KATP channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cytoplasmic terminus domains of Kir6.x confer different nucleotide-dependent gating on the ATP-sensitive K+ channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

ATP-sensitive K+ channels and insulin secretion: their role in health and disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Molecular biology of adenosine triphosphate-sensitive potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Function, regulation, pharmacology, and molecular structure of ATP-sensitive K+ channels in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Electrophysiology of the pancreatic beta-cell

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

ATP-sensitive and inwardly rectifying potassium channels in smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Mg2+ and ATP dependence of K(ATP) channel modulator binding to the recombinant sulphonylurea receptor, SUR2B.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Potassium channel openers require ATP to bind to and act through sulfonylurea receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Identification of the potassium channel opener site on sulfonylurea receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

The sulphonylurea receptor SUR1 regulates ATP-sensitive mouse Kir6.2 K+ channels linked to the green fluorescent protein in human embryonic kidney cells (HEK 293).

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Pharmaco-topology of sulfonylurea receptors. Separate domains of the regulatory subunits of K(ATP) channel isoforms are required for selective interaction with K(+) channel openers

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

A transmembrane domain of the sulfonylurea receptor mediates activation of ATP-sensitive K(+) channels by K(+) channel openers.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Nucleotide regulation and characteristics of potassium channel opener binding to skeletal muscle membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Different Binding Properties and Affinities for ATP and ADP among Sulfonylurea Receptor Subtypes, SUR1, SUR2A, and SUR2B

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Mechanism of action of K channel openers on skeletal muscle KATP channels. Interactions with nucleotides and protons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Intracellular nucleotide-mediated gating of SUR/Kir6.0 complex potassium channels expressed in a mammalian cell line and its modification by pinacidil.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

Stoichiometry of potassium channel opener action.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901563-7

7 January 2021

10.1016/S0165-6147(00)01563-7

Identifiers

DOI

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30 July 2017

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