(Q33937174)

30 July 2017

title

Activation of lecithin:cholesterol acyltransferase by HDL ApoA-I central helices (English)

1 reference

30 July 2017

Mary G Sorci-Thomas

1

1 reference

30 July 2017

Shaila Bhat

series ordinal

2

1 reference

30 July 2017

Michael J Thomas

series ordinal

3

1 reference

30 July 2017

publication date

1 February 2009

1 reference

30 July 2017

1 reference

30 July 2017

volume

4

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30 July 2017

issue

1

1 reference

30 July 2017

page(s)

113-124

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Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes

30 July 2017

cites work

1 reference

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5 July 2018

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The interplay between size, morphology, stability, and functionality of high-density lipoprotein subclasses

5 July 2018

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Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I.

5 July 2018

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5 July 2018

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Mild oxidation promotes and advanced oxidation impairs remodeling of human high-density lipoprotein in vitro

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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LCAT can rescue the abnormal phenotype produced by the natural ApoA-I mutations (Leu141Arg)Pisa and (Leu159Arg)FIN.

5 July 2018

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Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes

5 July 2018

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The structure of apolipoprotein A-I in high density lipoproteins.

5 July 2018

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Naturally occurring and bioengineered apoA-I mutations that inhibit the conversion of discoidal to spherical HDL: the abnormal HDL phenotypes can be corrected by treatment with LCAT.

5 July 2018

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Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy.

5 July 2018

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Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis

5 July 2018

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The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I.

5 July 2018

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Regulation of the activity and fatty acid specificity of lecithin-cholesterol acyltransferase by sphingomyelin and its metabolites, ceramide and ceramide phosphate

5 July 2018

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Novel changes in discoidal high density lipoprotein morphology: a molecular dynamics study.

5 July 2018

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Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL.

5 July 2018

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Crystal structure of human apolipoprotein A-I: insights into its protective effect against cardiovascular diseases.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Differential diagnosis of familial high density lipoprotein deficiency syndromes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Förster resonance energy transfer measurements are consistent with a helical bundle model for lipid-free apolipoprotein A-I.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

What is so special about apolipoprotein AI in reverse cholesterol transport?

5 July 2018

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ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease

5 July 2018

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Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Apolipoprotein structural organization in high density lipoproteins: belts, bundles, hinges and hairpins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

A three-dimensional molecular model of lipid-free apolipoprotein A-I determined by cross-linking/mass spectrometry and sequence threading.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Formation of methionine sulfoxide-containing specific forms of oxidized high-density lipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Triacylglycerol hydrolase: role in intracellular lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

ApoA-I structure on discs and spheres. Variable helix registry and conformational states

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

The effects of altered apolipoprotein A-I structure on plasma HDL concentration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Structural models of human apolipoprotein A-I: a critical analysis and review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Lecithin cholesterol acyltransferase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Relationship between structure and biochemical phenotype of lecithin:cholesterol acyltransferase (LCAT) mutants causing fish-eye disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

An amphipathic alpha-helix at a membrane interface: a structural study using a novel X-ray diffraction method.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Structural and functional properties of two mutants of lecithin-cholesterol acyltransferase (T123I and N228K)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): identification of the catalytic triad and molecular modeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Structural and functional properties of the 154-171 wild-type and variant peptides of human lecithin-cholesterol acyltransferase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Structural studies of a peptide activator of human lecithin-cholesterol acyltransferase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Lecithin-cholesterol acyltransferase: effects of mutagenesis at N-linked oligosaccharide attachment sites on acyl acceptor specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Lecithin:cholesterol acyltransferase: role of N-linked glycosylation in enzyme function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

The amphipathic alpha helix: a multifunctional structural motif in plasma apolipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Role of N-linked glycosylation of lecithin:cholesterol acyltransferase in lipoprotein substrate specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Mannitol prevents methionine sulphoxidation mediated electrophoretic heterogeneity of apolipoprotein A-I.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Site-specific detection and structural characterization of the glycosylation of human plasma proteins lecithin:cholesterol acyltransferase and apolipoprotein D using HPLC/electrospray mass spectrometry and sequential glycosidase digestion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

The plasma lecithins:cholesterol acyltransferase reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

A molecular theory of lipid-protein interactions in the plasma lipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Aromatic boronic acids as probes of the catalytic site of human plasma lecithin-cholesterol acyltransferase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

The apolipoprotein multigene family: structure, expression, evolution, and molecular genetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Structure-function relationships in human lecithin:cholesterol acyltransferase. Site-directed mutagenesis at serine residues 181 and 216.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Lecithin-cholesterol acyltransferase in the metabolism of high-density lipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Human Plasma Lecithin:Cholesterol Acyltransferase (LCAT) On the role of essential carboxyl groups in catalysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Site-specific methionine sulfoxide formation is the structural basis of chromatographic heterogeneity of apolipoproteins A-I, C-II, and C-III.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Environment-sensitive labels in multiplex fluorescence analyses of protein-DNA complexes

5 July 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Deletion of specific glycan chains affects differentially the stability, local structures, and activity of lecithin-cholesterol acyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Deletion of N-terminal amino acids from human lecithin:cholesterol acyltransferase differentially affects enzyme activity toward alpha- and beta-substrate lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

A dual role for lecithin:cholesterol acyltransferase (EC 2.3.1.43) in lipoprotein oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

A monomeric, biologically active, full-length human apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

The structure and interactions of human apolipoprotein C-II in dodecyl phosphocholine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Distinct central amphipathic alpha-helices in apolipoprotein A-I contribute to the in vivo maturation of high density lipoprotein by either activating lecithin-cholesterol acyltransferase or binding lipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Identification and structural ramifications of a hinge domain in apolipoprotein A-I discoidal high-density lipoproteins of different size

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

The spatial organization of apolipoprotein A-I on the edge of discoidal high density lipoprotein particles: a mass specrometry study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Structural and functional properties of apolipoprotein A-I mutants containing disulfide-linked cysteines at positions 124 or 232.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Oxidation of methionine residues affects the structure and stability of apolipoprotein A-I in reconstituted high density lipoprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Is the oxidation of high-density lipoprotein lipids different than the oxidation of low-density lipoprotein lipids?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891274

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

29 October 2018

1 reference

https://api.crossref.org/works/10.2217%2F17584299.4.1.113

Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer

21 January 2018

1 reference

12 December 2020

Lecithin-cholesterol acyltransferase (LCAT) catalyzes transacylation of intact cholesteryl esters. Evidence for the partial reversal of the forward LCAT reaction

1 reference

12 December 2020

Activation of Lecithin Cholesterol Acyltransferase by a Disulfide-Linked Apolipoprotein A-I Dimer

1 reference

12 December 2020

Identification of a domain of lecithin-cholesterol acyltransferase that is involved in interfacial recognition

1 reference

12 December 2020

The influence of sphingomyelin on the structure and function of reconstituted high density lipoproteins

1 reference

12 December 2020

Glycosylation structure and enzyme activity of lecithin:cholesterol acyltransferase from human plasma, HepG2 cells, and baculoviral and Chinese hamster ovary cell expression systems

1 reference

12 December 2020

Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice

1 reference

12 December 2020

Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein

1 reference

12 December 2020

Surface plasmon resonance biosensor studies of human wild-type and mutant lecithin cholesterol acyltransferase interactions with lipoproteins

1 reference

12 December 2020

Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII

1 reference

12 December 2020

Effects of site-directed mutagenesis on the N-glycosylation sites of human lecithin:cholesterol acyltransferase

1 reference

12 December 2020

Effects of site-directed mutagenesis on the serine residues of human lecithin:cholesterol acyltransferase

1 reference

12 December 2020

Apolipoprotein A-I structure and lipid properties in homogeneous, reconstituted spherical and discoidal high density lipoproteins

1 reference

12 December 2020

Identification of a sequence of apolipoprotein A-I associated with the activation of Lecithin:Cholesterol acyltransferase

1 reference

12 December 2020

Apolipoprotein A-I domains involved in lecithin-cholesterol acyltransferase activation. Structure:function relationships

1 reference

12 December 2020

Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis

1 reference

12 December 2020

Structural analysis of apolipoprotein A-I: limited proteolysis of methionine-reduced and -oxidized lipid-free and lipid-bound human apo A-I

1 reference

12 December 2020

A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein

1 reference

12 December 2020

Role of LCAT in HDL remodeling: investigation of LCAT deficiency states

1 reference

12 December 2020

The process of dissolving apolipoprotein A-I in an aqueous buffer

1 reference

12 December 2020

Sphingomyelin inhibits the lecithin-cholesterol acyltransferase reaction with reconstituted high density lipoproteins by decreasing enzyme binding

1 reference

12 December 2020

The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation

1 reference

12 December 2020

Effect of oxidation on the properties of apolipoproteins A-I and A-II

1 reference

12 December 2020

Characterization of recombinant human plasma lecithin: cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

1 reference

12 December 2020

Identifiers

DOI

10.2217/17584299.4.1.113

1 reference

30 July 2017

1 reference

30 July 2017

1 reference