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CCK-B antagonists in the control of anxiety and gastric acid secretion.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
CCK-B antagonists in the control of anxiety and gastric acid secretion
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
M S Chambers
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
S R Fletcher
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
publication date
1 January 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Progress in medicinal chemistry
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
37
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
45-81
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs
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Crossref
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7 January 2021
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Cholecystokinin and psychiatric disorders : role in aetiology and potential of receptor antagonists in therapy.
1 reference
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Crossref
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7 January 2021
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7 January 2021
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Neuropharmacology of anxiety: perspectives and prospects
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7 January 2021
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CCK in animal and human research on anxiety
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Crossref
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7 January 2021
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Replication of action of cholecystokinin tetrapeptide in panic disorder: clinical and behavioral findings
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7 January 2021
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The panicogenic effects of cholecystokinin-tetrapeptide are antagonized by L-365,260, a central cholecystokinin receptor antagonist, in patients with panic disorder
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reference URL
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7 January 2021
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Pentagastrin induced panic attacks: enhanced sensitivity in panic disorder patients
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Crossref
reference URL
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7 January 2021
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The CCKB receptor antagonist, L-365,260, elicits antidepressant-type effects in the forced-swim test in mice
1 reference
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Crossref
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7 January 2021
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Cholecystokinin and morphine analgesia: variations on a theme
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7 January 2021
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Cholecystokinin receptor binding in morphine analgesia: tolerance, withdrawal and abstinence.
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7 January 2021
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A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test
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Crossref
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7 January 2021
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Cholecystokinin antagonists--a toxicologic perspective
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7 January 2021
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Lack of effect of CCKB receptor antagonists in ethological and conditioned animal screens for anxiolytic drugs.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Failure of CCK receptor ligands to modify anxiety-related behavioural suppression in an operant conflict paradigm in rats.
1 reference
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Crossref
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7 January 2021
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Gastrin is a major mediator of the gastric phase of acid secretion in dogs: proof by monoclonal antibody neutralization
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7 January 2021
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Effect of gastrin receptor antagonists on gastric acid secretion and gastrin and somatostatin release in the rat stomach
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7 January 2021
based on heuristic
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Cholecystokinin-tetrapeptide induces panic attacks in patients with panic disorder
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cholecystokinin and anxiety in normal volunteers: an investigation of the anxiogenic properties of pentagastrin and reversal by the cholecystokinin receptor subtype B antagonist L-365,260
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
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inferred from DOI database lookup
Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
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A placebo-controlled trial of L-365,260, a CCKB antagonist, in panic disorder
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The cholecystokinin-B receptor antagonist CI-988 failed to affect CCK-4 induced symptoms in panic disorder patients
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
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inferred from DOI database lookup
Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile
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7 January 2021
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Characterization of antigastrin activity in vivo of CR 2194, a new R-4-benzamido-5-oxo-pentanoic acid derivative
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7 January 2021
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Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives
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7 January 2021
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The gastrin-receptor antagonist L-365,260 inhibits stimulated acid secretion in humans
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Crossref
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7 January 2021
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Benzodiazepine gastrin and brain cholecystokinin receptor ligands: L-365,260.
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7 January 2021
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Second-generation benzodiazepine CCK-B antagonists. Development of subnanomolar analogs with selectivity and water solubility
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7 January 2021
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Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
High-affinity and potent, water-soluble 5-amino-1,4-benzodiazepine CCKB/gastrin receptor antagonists containing a cationic solubilizing group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The cholecystokinin-B receptor antagonist L-740,093 produces an insurmountable antagonism of CCK-4 stimulated functional response in cells expressing the human CCK-B receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
(3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel 1,5-benzodiazepines as CCK-B ligands. Effect of aryl-carbamic substituents at the C-3 position together with halogen substitution on the benzo-fused ring
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and evaluation of 1,5-benzodiazepines with bridged cycloalkyl substituents at the N-1 position as potent and selective CCK-B Ligands
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and pharmacological characterization of the human CCKB receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Potent and subtype-selective CCK-B/gastrin receptor antagonists: 2,4-dioxo-1,5-benzodiazepines with a plane of symmetry
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and binding affinities of analogues of cholecystokinin-(30-33) as probes for central nervous system cholecystokinin receptors
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
On the biologically active structures of cholecystokinin, little gastrin, and enkephalin in the gastrointestinal system
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Are radioligand antagonist/agonist binding ratios in rat pancreas predictive of functional efficacy of cholecystokinin receptor agonists and antagonists?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of biologic gastrin activity of compound CI-988 in the isolated, vascularly perfused rat stomach
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quinazolinone cholecystokinin-B receptor ligands.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The use of receptor desensitization to analyse CCKA and CCKB/gastrin receptors coupled to contraction in guinea-pig stomach muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New 1,4-benzodiazepin-2-one derivatives as gastrin/cholecystokinin-B antagonists.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacological properties of ureido-acetamides, new potent and selective non-peptide CCKB/gastrin receptor antagonists.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors. II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and pharmacological properties of ureidomethylcarbamoylphenylketone derivatives. A new potent and subtype-selective nonpeptide CCK-B/gastrin receptor antagonist, S-0509.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The selective CCK-B receptor antagonist L-365,260 enhances morphine analgesia and prevents morphine tolerance in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new class of non-peptidic cholecystokinin-B/gastrin receptor antagonists based on dibenzobicyclo[2.2.2]octane
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Improving the affinity and selectivity of a nonpeptide series of cholecystokinin-B/gastrin receptor antagonists based on the dibenzobicyclo[2.2.2]octane skeleton
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Non-peptide cholecystokinin-B/gastrin receptor antagonists based on bicyclic, heteroaromatic skeletons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single amino acid of the cholecystokinin-B/gastrin receptor determines specificity for non-peptide antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antipsychotic potential of CCK-based treatments: an assessment using the prepulse inhibition model of psychosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-740,093, a new antagonist of the CCK-B receptor, potentiates the antinociceptive effect of morphine: electrophysiological and behavioural studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CCK in anxiety and cognitive processes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anxieties of drug discovery and development. CCK-B receptor antagonists.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970057-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0079-6468(08)70057-2
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
10845247
1 reference
stated in
Europe PubMed Central
PubMed ID
10845247
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10845247%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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