(Q33945101)

30 July 2017

title

Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease (English)

1 reference

metabolic dysfunction–associated steatotic liver disease

30 July 2017

main subject

1 reference

Matthew C Wheeler

1

1 reference

30 July 2017

Nicholas Gekakis

series ordinal

2

1 reference

30 July 2017

publication date

13 June 2014

1 reference

Journal of Lipid Research

30 July 2017

published in

1 reference

30 July 2017

volume

55

1 reference

30 July 2017

issue

8

1 reference

30 July 2017

page(s)

1702-1710

1 reference

Hsp90 blockers inhibit adipocyte differentiation and fat mass accumulation

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7.

5 July 2018

1 reference

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Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Mechanisms of Sec61/SecY-mediated protein translocation across membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Forming functional fat: a growing understanding of adipocyte differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Human fatty liver disease: old questions and new insights

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Non-alcoholic fatty liver disease proteomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Celastrols as inducers of the heat shock response and cytoprotection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Drug action of thapsigargin on the Ca2+ pump protein of sarcoplasmic reticulum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4109764

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

5 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M048918

Hsp90 chaperones PPARγ and regulates differentiation and survival of 3T3-L1 adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M048918

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M048918

Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M048918

Signalling through nuclear receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M048918

Relationship of the structure and biological activity of the natural homologues of tunicamycin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24927728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24927728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M048918

1 reference

30 July 2017

1 reference

30 July 2017

1 reference