(Q33946234)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

A yeast-based assay identifies drugs active against human mitochondrial disorders (English)

1 reference

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6 February 2020

3

1 reference

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6 February 2020

Julien Gagneur

6

1 reference

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6 February 2020

Lars M Steinmetz

11

1 reference

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6 February 2020

Marc Blondel

13

1 reference

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6 February 2020

author name string

Elodie Couplan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Raeka S Aiyar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Anna Kabala

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Nahia Ezkurdia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Robert P St Onge

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Bénédicte Salin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Flavie Soubigou

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Marie Le Cann

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Jean-Paul di Rago

12

1 reference

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6 February 2020

language of work or name

English

0 references

publication date

29 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

1 reference

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6 February 2020

volume

108

1 reference

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6 February 2020

issue

29

1 reference

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6 February 2020

page(s)

11989-11994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

Mitochondrial DNA mutations and human disease

6 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Introducing the human Leigh syndrome mutation T9176G into Saccharomyces cerevisiae mitochondrial DNA leads to severe defects in the incorporation of Atp6p into the ATP synthase and in the mitochondrial morphology.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Antiprion drugs as chemical tools to uncover mechanisms of prion propagation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Tools for the study of ribosome-borne protein folding activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

A yeast model of the neurogenic ataxia retinitis pigmentosa (NARP) T8993G mutation in the mitochondrial ATP synthase-6 gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Biochemical phenotypes associated with the mitochondrial ATP6 gene mutations at nt8993.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Yeast models of human mitochondrial diseases: from molecular mechanisms to drug screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

A yeast-based assay to isolate drugs active against mammalian prions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Mitochondrial diseases and genetic defects of ATP synthase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

A high-resolution map of transcription in the yeast genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

High-efficiency biolistic transformation of Chlamydomonas mitochondria can be used to insert mutations in complex I genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

An improved map of conserved regulatory sites for Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Mitochondrial threshold effects.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Genome-wide responses to mitochondrial dysfunction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Gene ontology: tool for the unification of biology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Supercomplexes in the respiratory chains of yeast and mammalian mitochondria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Oligomycin induces a decrease in the cellular content of a pathogenic mutation in the human mitochondrial ATPase 6 gene.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

The kinetic basis of threshold effects observed in mitochondrial diseases: a systemic approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

19 Preparation of yeast mitochondria (Saccharomyces cerevisiae) with good P/O and respiratory control ratios

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

The Effect of Chlorhexidine on some Biochemical Parameters of Rat Liver Mitochondria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Consequences of the pathogenic T9176C mutation of human mitochondrial DNA on yeast mitochondrial ATP synthase

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Approaches to the treatment of mitochondrial diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Cellular and functional analysis of four mutations located in the mitochondrial ATPase6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Yeast mitochondrial oxodicarboxylate transporters are important for growth on oleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Isolation of drugs active against mammalian prions using a yeast-based screening assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Failure to assemble the alpha 3 beta 3 subcomplex of the ATP synthase leads to accumulation of the alpha and beta subunits within inclusion bodies and the loss of mitochondrial cristae in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

ATO3 encoding a putative outward ammonium transporter is an RTG-independent retrograde responsive gene regulated by GCN4 and the Ssy1-Ptr3-Ssy5 amino acid sensor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

The Mg2+ requirements for rho transcription termination factor: catalysis and bicyclomycin inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Impact on oxidative phosphorylation of immortalization with the telomerase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101478108

Biochemical consequences in yeast of the human mitochondrial DNA 8993T>C mutation in the ATPase6 gene found in NARP/MILS patients

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Mitochondrial ATP synthase disorders: molecular mechanisms and the quest for curative therapeutic approaches

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3141935

Genetic transformation of Saccharomyces cerevisiae mitochondria

29 October 2018

1 reference

12 December 2020

The biogenesis and assembly of photosynthetic proteins in thylakoid membranes1

1 reference

12 December 2020

Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform

1 reference

12 December 2020

Level of ATP synthase activity required for yeast Saccharomyces cerevisiae to grow on glycerol media

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1101478108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21715656%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference