(Q33947768)

30 July 2017

title

Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery (English)

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30 July 2017

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D J. Payne

1

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30 July 2017

P V. Warren

2

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30 July 2017

D J. Holmes

3

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30 July 2017

Y Ji

4

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30 July 2017

J T. Lonsdale

5

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30 July 2017

publication date

1 May 2001

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

10

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30 July 2017

page(s)

537-544

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More extended-spectrum beta-lactamases

30 July 2017

cites work

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Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci

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Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities

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Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

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7 January 2021

Fatty acid synthase, a proficient multifunctional enzyme

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7 January 2021

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

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7 January 2021

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

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Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

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7 January 2021

The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis

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7 January 2021

Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene

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7 January 2021

Characterization of a Pseudomonas aeruginosa fatty acid biosynthetic gene cluster: purification of acyl carrier protein (ACP) and malonyl-coenzyme A:ACP transacylase (FabD)

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Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis

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A genomic analysis of two-component signal transduction in Streptococcus pneumoniae

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7 January 2021

A mechanism of drug action revealed by structural studies of enoyl reductase

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7 January 2021

Thiolactomycin, a new antibiotic. IV. Biological properties and chemotherapeutic activity in mice.

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7 January 2021

Triclosan targets lipid synthesis

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7 January 2021

Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

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7 January 2021

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

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7 January 2021

Development of a scintillation proximity assay for beta-ketoacyl-acyl carrier protein synthase III.

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7 January 2021

Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis

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7 January 2021

Refined structures of beta-ketoacyl-acyl carrier protein synthase III

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7 January 2021

Molecular basis for triclosan activity involves a flipping loop in the active site

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7 January 2021

Mechanism of triclosan inhibition of bacterial fatty acid synthesis

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7 January 2021

Molecular basis of triclosan activity

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7 January 2021

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

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7 January 2021

Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action

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7 January 2021

10.1016/S1359-6446(01)01774-3

Identifiers

DOI

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30 July 2017

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