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Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
title
Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme
(English)
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
main subject
glutathione
1 reference
based on heuristic
inferred from title
author
Andrew M Gulick
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
author name string
W E Fahl
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
language of work or name
English
0 references
publication date
1 August 1995
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
volume
92
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
page(s)
8140-8144
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
issue
18
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
cites work
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PubMed Central
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Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes
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PubMed Central
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Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase
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PubMed Central
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5 July 2018
Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
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PubMed Central
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Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines.
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Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient.
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Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards
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The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione
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Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents
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The enzymes of detoxication
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PubMed Central
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5 July 2018
Expression in Escherichia coli of rat liver cytosolic glutathione S-transferase Yc cDNA.
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5 July 2018
The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution
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Theta, a new class of glutathione transferases purified from rat and man
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Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine
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5 July 2018
The three-dimensional structure of a glutathione S-transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-A resolution
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5 July 2018
Site-directed mutagenesis of glutathione S-transferase YaYa. Important roles of tyrosine 9 and aspartic acid 101 in catalysis
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Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1
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5 July 2018
Glutathione peroxidase activity in selenium-deficient rat liver
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Kinetic analysis of the reaction of melphalan with water, phosphate, and glutathione.
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PubMed Central
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Glutathione and glutathione-dependent enzymes in ovarian adenocarcinoma cell lines derived from a patient before and after the onset of drug resistance: intrinsic differences and cell cycle effects.
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29 October 2018
Structural studies on human glutathione S-transferase pi. Substitution mutations to determine amino acids necessary for binding glutathione
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
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based on heuristic
inferred from PubMed ID database lookup
Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Three-dimensional structure of class π glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 Å resolution
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective modification of glutathione metabolism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of melphalan-glutathione adducts whose formation is catalyzed by glutathione transferases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Structural studies on human glutathione S-transferase pi. Family of native-specific monoclonal antibodies used to block catalysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7667259
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.92.18.8140
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
ADS bibcode
1995PNAS...92.8140G
0 references
PMCID
41111
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
PubMed ID
7667259
1 reference
stated in
Europe PubMed Central
PMCID
41111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7667259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
ResearchGate publication ID
15532417
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