(Q33952743)

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hCG-induced endoplasmic reticulum stress triggers apoptosis and reduces steroidogenic enzyme expression through activating transcription factor 6 in Leydig cells of the testis

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Europe PubMed Central

PubMed publication ID

30 July 2017

hCG-induced endoplasmic reticulum stress triggers apoptosis and reduces steroidogenic enzyme expression through activating transcription factor 6 in Leydig cells of the testis (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

endoplasmic reticulum

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author name string

Sun-Ji Park

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Tae-Shin Kim

2

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30 July 2017

Choon-Keun Park

3

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Europe PubMed Central

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30 July 2017

Sang-Hee Lee

4

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30 July 2017

Jin-Man Kim

5

1 reference

Europe PubMed Central

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30 July 2017

Kyu-Sun Lee

6

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30 July 2017

In-Kyu Lee

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Jeen-Woo Park

8

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Europe PubMed Central

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30 July 2017

Mark A Lawson

9

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30 July 2017

Dong-Seok Lee

10

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30 July 2017

publication date

15 February 2013

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30 July 2017

Journal of Molecular Endocrinology

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Europe PubMed Central

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30 July 2017

50

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Europe PubMed Central

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30 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

151-166

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Endoplasmic reticulum stress and insulin biosynthesis: a review

1 reference

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Endoplasmic reticulum stress and pancreatic β-cell death

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Endoplasmic reticulum stress in liver disease

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Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases cAMP-stimulated hepatic gluconeogenesis via inhibition of CREB.

1 reference

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Real-time in vivo bioluminescence imaging of lentiviral vector-mediated gene transfer in mouse testis

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Leydig cells: From stem cells to aging

1 reference

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GNRH induces the unfolded protein response in the LbetaT2 pituitary gonadotrope cell line

1 reference

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5 July 2018

Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner

1 reference

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5 July 2018

Endoplasmic reticulum stress: signaling the unfolded protein response

1 reference

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5 July 2018

Mediators of endoplasmic reticulum stress-induced apoptosis

1 reference

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5 July 2018

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

1 reference

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5 July 2018

From acute ER stress to physiological roles of the Unfolded Protein Response

1 reference

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5 July 2018

The mammalian unfolded protein response

1 reference

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5 July 2018

Involvement of protein kinase C and cyclic adenosine 3',5'-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells

1 reference

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5 July 2018

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

1 reference

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5 July 2018

The role of hCG in reproductive medicine

1 reference

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5 July 2018

Cell biology of Leydig cells in the testis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

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Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells

1 reference

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Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation

1 reference

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5 July 2018

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

1 reference

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5 July 2018

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

1 reference

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5 July 2018

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

5 July 2018

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4111658

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Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

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Recent concepts in the management of male infertility

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Establishment of gonadotropin-responsive murine leydig tumor cell line

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5 July 2018

Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis

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29 October 2018

N‐acetylcysteine counteracts oxidative stress and prevents hCG‐induced apoptosis in rat Leydig cells through down regulation of caspase‐8 and JNK

1 reference

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29 October 2018

Adverse effects associated with persistent stimulation of Leydig cells with hCG in vitro.

1 reference

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Bacterial endotoxin lipopolysaccharide and reactive oxygen species inhibit Leydig cell steroidogenesis via perturbation of mitochondria

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The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice

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Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.

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Maintenance of spermatogenesis in hypogonadotropic hypogonadal men with human chorionic gonadotropin alone.

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Differential modulation of apoptotic gene expression by N-acetyl-L-cysteine in Leydig cells stimulated persistently with hCG in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

12 December 2020

based on heuristic

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Administration of human chorionic gonadotropin with a controlled-release function to immature rats for application in male infertility therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

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inferred from PubMed ID database lookup

The pattern of gonadotropin-induced change in plasma testosterone, testicular esterified cholesterol and Leydig cell lipid droplets in immature mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

hCG treatment raises H2O2 levels and induces germ cell apoptosis in rat testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lutropin/choriogonadotropin receptor, a 2002 perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/23256993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1530/JME-12-0195

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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