(Q33952780)

English

The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis (English)

1 reference

Europe PubMed Central

30 July 2017

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1 reference

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author name string

X Jiang

1

1 reference

Europe PubMed Central

30 July 2017

J N Buxbaum

2

1 reference

Europe PubMed Central

30 July 2017

J W Kelly

3

1 reference

Europe PubMed Central

30 July 2017

language of work or name

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publication date

1 December 2001

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

30 July 2017

98

1 reference

Europe PubMed Central

30 July 2017

14943-14948

1 reference

Europe PubMed Central

30 July 2017

26

1 reference

Europe PubMed Central

30 July 2017

Support for the multigenic hypothesis of amyloidosis: the binding stoichiometry of retinol-binding protein, vitamin A, and thyroid hormone influences transthyretin amyloidogenicity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Strand-Specific Postreplicative Processing of Mammalian Telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Legume lectin family, the 'natural mutants of the quaternary state', provide insights into the relationship between protein stability and oligomerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Transthyretin slowly exchanges subunits under physiological conditions: A convenient chromatographic method to study subunit exchange in oligomeric proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

The role of tetramerization in p53 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Subunit-subunit interactions in trimeric arginase. Generation of active monomers by mutation of a single amino acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Plasticity of quaternary structure: twenty-two ways to form a LacI dimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

A glimpse of a possible amyloidogenic intermediate of transthyretin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Review: immunoglobulin light chain amyloidosis--the archetype of structural and pathogenic variability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Immunoglobulin light chains, glycosaminoglycans, and amyloid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

The genetics of the amyloidoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Late-onset familial amyloid polyneuropathy type I (transthyretin Met30-associated familial amyloid polyneuropathy) unrelated to endemic focus in Japan. Clinicopathological and genetic features.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Protein misfolding, evolution and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Protein aggregation: folding aggregates, inclusion bodies and amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Alzheimer's disease: genotypes, phenotypes, and treatments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Alternative conformations of amyloidogenic proteins govern their behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Ultraviolet refractive indices of aqueous solutions of urea and guanidine hydrochloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

The pathogenesis and biochemistry of amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Systemic senile amyloidosis. Identification of a new prealbumin (transthyretin) variant in cardiac tissue: immunologic and biochemical similarity to one form of familial amyloidotic polyneuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Fibril in senile systemic amyloidosis is derived from normal transthyretin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Genetic Aspects of Amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

5 July 2018

Transthyretin isoleucine-122 mutation in African and American blacks

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

Revised transthyretin Ile 122 allele frequency in African-Americans

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

A single mutation disrupts the pH-dependent dimerization of glycinamide ribonucleotide transformylase

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

Structure of the Val122Ile variant transthyretin - a cardiomyopathic mutant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64963

29 October 2018

Sequence Communication: Tabulation of transthyretin (TTR) variants as of 1/1/2000

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

A chemical approach to elucidate tin mechanism of transthyretin and β-protein amyloid fibril formation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261419998

21 January 2018

Comparative Studies of Two Transthyretin Variants with Protective Effects on Familial Amyloidotic Polyneuropathy: TTR R104H and TTR T119M

1 reference

https://pubmed.ncbi.nlm.nih.gov/11752443

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/11752443

12 December 2020

based on heuristic

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Identifiers

10.1073/PNAS.261419998

1 reference

Europe PubMed Central

30 July 2017

2001PNAS...9814943J

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24 November 2022

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Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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