(Q33952952)

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Role of the GABA(A)beta2, GABA(A)alpha6, GABA(A)alpha1 and GABA(A)gamma2 receptor subunit genes cluster in drug responses and the development of alcohol dependence

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Europe PubMed Central

Role of the GABA(A)beta2, GABA(A)alpha6, GABA(A)alpha1 and GABA(A)gamma2 receptor subunit genes cluster in drug responses and the development of alcohol dependence (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

alcohol dependence

1 reference

based on heuristic

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author name string

Loh EW

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ball D

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

1 November 2000

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Europe PubMed Central

PubMed publication ID

30 July 2017

Neurochemistry International

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Europe PubMed Central

PubMed publication ID

30 July 2017

37

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Europe PubMed Central

PubMed publication ID

30 July 2017

5-6

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Europe PubMed Central

PubMed publication ID

30 July 2017

413-423

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Genomic mapping and evolution of human GABA A receptor subunit gene clusters

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human neuronal gamma-aminobutyric acid(A) receptors: coordinated subunit mRNA expression and functional correlates in individual dentate granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Stoichiometry of a recombinant GABAA receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Polymorphisms and intron sequences flanking the alternatively spliced 8-amino-acid exon of gamma2 subunit gene for GABAA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Why different rules are required for polygenic inheritance: lessons from studies of the DRD2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of GABAA receptor sites that are photoaffinity-labelled by [3H]flunitrazepam and [3H]Ro 15-4513.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Alcohol Dependence Produced in Mice by Inhalation of Ethanol: Grading the Withdrawal Reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ethanol increases GABAA responses in cells stably transfected with receptor subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Further evidence for clustering of human GABAA receptor subunit genes: localization of the alpha 6-subunit gene (GABRA6) to distal chromosome 5q by linkage analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Search for mutations near the alternatively spliced 8-amino-acid exon in the GABAA receptor gamma 2 subunit gene and lack of allelic association with alcoholism among four aboriginal groups and Han Chinese in Taiwan.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Rand Lecture, ASCEPT. GABA receptors: as complex as ABC? Australaisian Society for Clinical and Experimental Pharmacologists and Toxicologists

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligonucleotide to GABAA receptor gamma 2 subunit induces loss of neurones in rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The subunit composition of a GABAA/benzodiazepine receptor from rat cerebellum.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tolerance to ethanol and cross-tolerance to pentobarbital and barbital in four rat strains

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of lipid solubility on the development of chronic cross-tolerance between ethanol and different alcohols and barbiturates

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of Two Forms of the ?-Aminobutyric AcidAReceptor ?-2-Subunit in Mice by Alternative Splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hormone responses to sedative drugs and cold exposure in two rat lines with high and low alcohol sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cerebellar granule-cell-specific GABAA receptors attenuate benzodiazepine-induced ataxia: evidence from alpha 6-subunit-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

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The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

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The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tolerance to and cross-tolerance among ethanol, pentobarbital and chlordiazepoxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association analysis of the GABA(A) receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotypic and Genotypic Analysis of Rats with Cerebellar GABAA Receptors Composed from Mutant and Wild‐Type α6 Subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular size of the gamma-aminobutyric acidA receptor purified from mammalian cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic ethanol administration increases the binding of the benzodiazepine inverse agonist and alcohol antagonist [3H]RO15-4513 in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Alcohol challenge with sons of alcoholics: a critical review and analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

D2 dopamine receptor and GABAA receptor β3 subunit genes and alcoholism

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The alpha 6 subunit of the GABAA receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the alpha6 subunit gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular biology of GABAA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Gamma-aminobutyric acid, bicuculline, and post-synaptic binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

GABA-dopamine receptor-receptor interactions in neostriatal membranes of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative characterization of alpha 6 and alpha 1 alpha 6 subunit-containing native gamma-aminobutyric acidA receptors of adult rat cerebellum demonstrates two alpha subunits per receptor oligomer

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Meta-analysis of subjective sensitivity to alcohol in sons of alcoholics

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

An 8-year follow-up of 450 sons of alcoholic and control subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Biological, psychological and environmental predictors of the alcoholism risk: a longitudinal study.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha 6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of subunit composition of rat brain GABAA receptors on channel function

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant GABAA receptor function and ethanol

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of ethanol on hippocampal GABA receptors in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of GABAA receptor alpha 5 and alpha 6 subunit-like immunoreactivity in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional properties of GABAA receptors in two rat lines selected for high and low alcohol sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

GABAA/benzodiazepine receptor alpha 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ethanol potentiation of GABAA receptors requires phosphorylation of the alternatively spliced variant of the gamma 2 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Strain comparisons and developmental profile of the delta subunit of the murine GABAA receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The cerebellum: a model system for studying GABAA receptor diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of the human GABAA receptor alpha 4 subunit: identification of a unique diazepam-insensitive binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental expression of the alpha 6 GABAA receptor subunit mRNA occurs only after cerebellar granule cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Delta subunit inhibits neurosteroid modulation of GABAA receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2800%2900054-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0197-0186(00)00054-1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

release_3uysdyaikjc7per3elm5puf7qm

1 reference

https://api.fatcat.wiki/v0/release/3uysdyaikjc7per3elm5puf7qm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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