(Q33954631)

30 July 2017

title

Species and gender differences affect the metabolism of emodin via glucuronidation (English)

1 reference

30 July 2017

Wei Liu

1

1 reference

30 July 2017

Lan Tang

2

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30 July 2017

Ling Ye

3

1 reference

30 July 2017

Zheng Cai

4

1 reference

30 July 2017

Bijun Xia

5

1 reference

30 July 2017

Jiajie Zhang

6

1 reference

30 July 2017

Ming Hu

7

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30 July 2017

Zhongqiu Liu

8

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30 July 2017

language of work or name

English

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publication date

14 May 2010

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30 July 2017

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30 July 2017

volume

12

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30 July 2017

issue

3

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30 July 2017

page(s)

424-436

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https://scigraph.springernature.com/pub.10.1208/s12248-010-9200-6

30 July 2017

exact match

0 references

cites work

Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones

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Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney

5 July 2018

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Structural elucidation of in vitro metabolites of emodin by liquid chromatography-tandem mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Anti-cancer properties of anthraquinones from rhubarb

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Chemosensitization and radiosensitization of tumors by plant polyphenols

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Simultaneous determination of all polyphenols in vegetables, fruits, and teas

5 July 2018

1 reference

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Atypical kinetic profiles in drug metabolism reactions

5 July 2018

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Targeting HER2: recent developments and future directions for breast cancer patients

5 July 2018

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In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model

5 July 2018

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Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: effect of different drugs.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

2-Hydroxyemodin, an active metabolite of emodin in the hepatic microsomes of rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach.

5 July 2018

1 reference

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Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Immunosuppressive effect of emodin, a free radical generator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Mutagenicity of substituted anthraquinones in the Ames/Salmonella microsome system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

A theoretical study on interactions between mitoxantrone as an anticancer drug and DNA: application in drug design.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Disposition of flavonoids via enteric recycling: structural effects and lack of correlations between in vitro and in situ metabolic properties.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Gender difference in serum bisphenol A levels may be caused by liver UDP-glucuronosyltransferase activity in rats

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Microsomal transformation of emodin into a direct mutagen

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Cytotoxic and mutagenic effects of emodin on cultured mouse carcinoma FM3A cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895442

Metabolism of [14C]emodin in the rat

29 October 2018

1 reference

12 December 2020

Determination of absorption characteristics of AG337, a novel thymidylate synthase inhibitor, using a perfused rat intestinal model

1 reference

12 December 2020

Cellular absorption of anthraquinones emodin and chrysophanol in human intestinal Caco-2 cells

1 reference

12 December 2020

Pharmacokinetics of [(14)C]Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health

1 reference

12 December 2020

10.1208/S12248-010-9200-6

Identifiers

DOI

1 reference

Dimensions Publication ID

30 July 2017

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1 reference

30 July 2017

1 reference