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Cyclosporin A promotes translational silencing of autocrine interleukin-3 via ribosome-associated deadenylation
scientific article
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instance of
scholarly article
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
title
Cyclosporin A promotes translational silencing of autocrine interleukin-3 via ribosome-associated deadenylation
(English)
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
main subject
cyclosporine
1 reference
based on heuristic
inferred from title
author name string
A P Nair
series ordinal
1
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
H H Hirsch
series ordinal
2
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
M Colombi
series ordinal
3
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
C Moroni
series ordinal
4
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
language of work or name
English
0 references
publication date
1 January 1999
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
published in
Molecular and Cellular Biology
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
volume
19
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
page(s)
889-898
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
issue
1
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
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Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region
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Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E
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Autocrine transformation of hemopoietic cells resulting from cytokine message stabilization after intracisternal A particle transposition
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Use of the CTL44 cell line, a derivative of CTL/L cells, to identify and quantify mouse interleukin-4 by bioassay
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5 July 2018
Suppressible and nonsuppressible autocrine mast cell tumors are distinguished by insertion of an endogenous retroviral element (IAP) into the interleukin 3 gene
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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
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Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation
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5 July 2018
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5 July 2018
AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay.
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5 July 2018
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
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AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity
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5 July 2018
The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation
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PubMed Central
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mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation
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5 July 2018
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PubMed Central
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5 July 2018
Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia
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PubMed Central
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5 July 2018
A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
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PubMed Central
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5 July 2018
Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system
1 reference
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PubMed Central
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5 July 2018
A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Identification of genes involved in growth autonomy of hematopoietic cells by analysis of factor-independent mutants
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Regulation of c-myc mRNA stability in vitro by a labile destabilizer with an essential nucleic acid component
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro
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PubMed Central
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5 July 2018
Tumor suppression involves down-regulation of interleukin 3 expression in hybrids between autocrine mastocytoma and interleukin 3-dependent parental mast cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production
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PubMed Central
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5 July 2018
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
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5 July 2018
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
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5 July 2018
Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes
1 reference
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PubMed Central
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5 July 2018
Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
DNA rearrangement and constitutive expression of the interleukin 6 gene in a mouse plasmacytoma
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
Cytokine messenger RNA stability is enhanced in tumor cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
retrieved
5 July 2018
Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
retrieved
5 July 2018
Mutations affecting stability and deadenylation of the yeast MFA2 transcript
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
retrieved
5 July 2018
Mast cells sensitive to v-H-ras transformation are hyperinducible for interleukin 3 expression and have lost tumor-suppressor activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
The mechanism of action of cyclosporin A and FK506
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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5 July 2018
3'-UTR-dependent deadenylation by the yeast poly(A) nuclease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
retrieved
5 July 2018
Identification of an AUUUA-specific messenger RNA binding protein
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83946
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29 October 2018
Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mechanisms of mRNA degradation in eukaryotes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
c-fos mRNA instability determinants present within both the coding and the 3' non coding region link the degradation of this mRNA to its translation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Impaired interleukin-3 mRNA decay in autocrine mast cell tumors after transient calcium ionophore stimulation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858612
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.1.889
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
PMCID
83946
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
PubMed ID
9858612
1 reference
stated in
Q5412157
PubMed ID
9858612
retrieved
30 July 2017
ResearchGate publication ID
13428422
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