(Q33958925)

30 July 2017

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title

Molecular mechanisms of cancer pain (English)

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30 July 2017

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Patrick W Mantyh

1

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30 July 2017

Denis R Clohisy

series ordinal

2

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30 July 2017

Martin Koltzenburg

series ordinal

3

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30 July 2017

Steve P Hunt

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 March 2002

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30 July 2017

Nature Reviews Cancer

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30 July 2017

2

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30 July 2017

201-209

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30 July 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrc747

30 July 2017

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31 March 2020

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The Amsterdam Pain Management Index compared to eight frequently used outcome measures to evaluate the adequacy of pain treatment in cancer patients with chronic pain

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Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain

31 March 2020

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Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord

31 March 2020

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Association of somatic action potential shape with sensory receptive properties in guinea-pig dorsal root ganglion neurones

31 March 2020

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Molecular mechanisms of nociception

31 March 2020

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Inhibition of rapid heat responses in nociceptive primary sensory neurons of rats by vanilloid receptor antagonists

31 March 2020

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The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat

31 March 2020

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Protons: small stimulants of capsaicin-sensitive sensory nerves

31 March 2020

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Impaired nociception and pain sensation in mice lacking the capsaicin receptor

31 March 2020

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Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons.

31 March 2020

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The cloned capsaicin receptor integrates multiple pain-producing stimuli

31 March 2020

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The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice

31 March 2020

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Cationic channels activated by extracellular ATP in rat sensory neurons.

31 March 2020

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Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons.

31 March 2020

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Nociceptors for the 21st century

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NGF as a mediator of inflammatory pain.

31 March 2020

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Neuronal plasticity: increasing the gain in pain

31 March 2020

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Novel classes of responsive and unresponsive C nociceptors in human skin

31 March 2020

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Cellular and neurochemical remodeling of the spinal cord in bone cancer pain

31 March 2020

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Neurochemical plasticity in persistent inflammatory pain

31 March 2020

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Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo

31 March 2020

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Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation

31 March 2020

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The molecular dynamics of pain control

31 March 2020

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Differential effects of morphine on noxious stimulus-evoked fos-like immunoreactivity in subpopulations of spinoparabrachial neurons.

31 March 2020

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Substance P receptor (neurokinin-1)-expressing neurons in lamina I of the spinal cord encode for the intensity of noxious stimulation: a c-Fos study in rat

31 March 2020

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Induction of c-fos-like protein in spinal cord neurons following sensory stimulation

31 March 2020

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Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentanil and lidocaine

31 March 2020

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Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons

31 March 2020

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Bone metastases: pathophysiology and management policy

31 March 2020

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The role of neuroinflammation and neuroimmune activation in persistent pain

31 March 2020

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Immune activation: the role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states

31 March 2020

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Implications of immune-to-brain communication for sickness and pain

31 March 2020

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IL-1beta and TNF-alpha in prostatic secretions are indicators in the evaluation of men with chronic prostatitis

31 March 2020

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Endothelin-1 and metastatic cancer pain

31 March 2020

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Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1 beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin.

31 March 2020

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Mechanisms of tumor necrosis factor-alpha (TNF-alpha) hyperalgesia

31 March 2020

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Clinical implications of circulating angiogenic factors in cancer patients

31 March 2020

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TGF-beta and colorectal carcinogenesis

31 March 2020

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Prostaglandin-induced neuropeptide release from spinal cord.

31 March 2020

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Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma

31 March 2020

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Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer

31 March 2020

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Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma

31 March 2020

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Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

31 March 2020

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COX-2 inhibition, apoptosis, and chemoprevention by nonsteroidal anti-inflammatory drugs

31 March 2020

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Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia

31 March 2020

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The use of anti-inflammatory drugs in cancer pain

31 March 2020

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Raised endothelin 1 levels in patients with colorectal liver metastases.

31 March 2020

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Endothelin-secreting tumors and the idea of the pseudoectopic hormone secretion in tumors

31 March 2020

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Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate

31 March 2020

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Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception

31 March 2020

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Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve.

31 March 2020

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Endothelin-1 and tumour development

31 March 2020

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31 March 2020

Are cancer cells acidic?

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Chapter 8. Tissue acidosis in nociception and pain

31 March 2020

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Chemical mediators of pain due to tissue damage and ischemia

31 March 2020

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An acid sensing ion channel (ASIC) localizes to small primary afferent neurons in rats

31 March 2020

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

31 March 2020

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The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties

31 March 2020

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A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells

31 March 2020

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Review of cellular mechanisms of tumor osteolysis.

31 March 2020

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Osteoprotegerin inhibits tumor-induced osteoclastogenesis and bone tumor growth in osteopetrotic mice

31 March 2020

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Pamidronate decreases tumor-induced osteoclastogenesis in osteopetrotic mice

31 March 2020

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Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites

31 March 2020

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Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases

31 March 2020

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The role of bisphosphonates in the treatment of painful metastatic bone disease: a review of phase III trials

31 March 2020

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New bisphosphonates in the treatment of bone diseases

31 March 2020

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Therapeutic approaches to bone diseases

31 March 2020

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Actions of bisphosphonate on bone metastasis in animal models of breast carcinoma

31 March 2020

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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

31 March 2020

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A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

31 March 2020

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

31 March 2020

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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

31 March 2020

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The effect of a single dose of osteoprotegerin in postmenopausal women

31 March 2020

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S-100-positive nerve fibers in hepatocellular carcinoma and intrahepatic cholangiocarcinoma: an immunohistochemical study

31 March 2020

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Tumours may be innervated

31 March 2020

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Strategies for the treatment of cancer pain in the new millennium

31 March 2020

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Taxol produces a predominantly sensory neuropathy

31 March 2020

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A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel

31 March 2020

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Chemotherapy-evoked painful peripheral neuropathy

31 March 2020

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Altered expressions of glutamate transporter subtypes in rat model of neonatal cerebral hypoxia-ischemia

31 March 2020

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Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

31 March 2020

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Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors

31 March 2020

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Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone

31 March 2020

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Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin

31 March 2020

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Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy

31 March 2020

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Dynorphin expression and Fos-like immunoreactivity following inflammation induced hyperalgesia are colocalized in spinal cord neurons

31 March 2020

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Activity-dependent neuronal plasticity following tissue injury and inflammation

31 March 2020

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Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization

31 March 2020

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The up-regulation of preprodynorphin mRNA in trigeminoparabrachial neurons after inflammation

31 March 2020

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Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesia

31 March 2020

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A visceral pain pathway in the dorsal column of the spinal cord

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC747

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Dimensions Publication ID

30 July 2017

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1 reference