(Q33959052)

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Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2 (English)

1 reference

Europe PubMed Central

30 July 2017

author name string

S Uma

1

1 reference

Europe PubMed Central

30 July 2017

V Thulasiraman

2

1 reference

Europe PubMed Central

30 July 2017

R L Matts

3

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

1 September 1999

1 reference

Europe PubMed Central

30 July 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

30 July 2017

19

1 reference

Europe PubMed Central

30 July 2017

5861-5871

1 reference

Europe PubMed Central

30 July 2017

9

1 reference

Europe PubMed Central

30 July 2017

The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

In vivo newly translated polypeptides are sequestered in a protected folding environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Characterization of the hemin-sensitive eukaryotic initiation factor 2alpha kinase from mouse nonerythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Luciferase renaturation assays of chaperones and chaperone antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Regulation of the heat shock conjugate Hsc70 in the mammalian cell: the characterization of the anti-apoptotic protein BAG-1 provides novel insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

The Hsp70 and Hsp60 chaperone machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Steroid receptor interactions with heat shock protein and immunophilin chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Hsp90-mediated folding of the lymphoid cell kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Molecular chaperones in cellular protein folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Association of peroxisome proliferator-activated receptor and Hsp72.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Regulation of 70-kDa heat-shock-protein ATPase activity and substrate binding by human DnaJ-like proteins, HSJ1a and HSJ1b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Cloning and characterization of cDNA encoding rat hemin-sensitive initiation factor-2 alpha (eIF-2 alpha) kinase. Evidence for multitissue expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Independent signaling of grp78 gene transcription and phosphorylation of eukaryotic initiator factor 2 alpha by the stressed endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Modulators of the eukaryotic heat shock response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Mechanism of drug-induced heat resistance: the role of protein degradation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Translational control in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

Is hsp70 the cellular thermometer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

The relationship between protein synthesis and heat shock proteins levels in rabbit reticulocyte lysates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

5 July 2018

HSP70-2 heat-shock protein of mouse spermatogenic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

29 October 2018

Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84435

29 October 2018

Protection of Chinese hamster ovary cells from hyperthermic killing by cycloheximide or puromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Denatured proteins inhibit translation in hemin-supplemented rabbit reticulocyte lysate by inducing the activation of the heme-regulated eIF-2 alpha kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of Hsp90 with cellular Src-family kinases in a cell-free system correlates with altered kinase structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of protein synthesis by hemin. Purification of a rabbit reticulocyte hsp 70 and characterization of its regulation of the activation of the hemin-controlled eIF-2(alpha) kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of protein phosphorylation state by a combination of vertical slab gel isoelectric focusing and immunoblotting

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that Hsc70 negatively modulates the activation of the heme-regulated eIF-2alpha kinase in rabbit reticulocyte lysate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme-regulated eIF-2alpha kinase purifies as a hemoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of globin synthesis: The role of heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that glucose 6-phosphate regulates protein synthesis initiation in reticulocyte lysates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of initiation of protein synthesis by phosphorylation of eIF-2(alpha) and the role of reversing factor in the recycling of eIF-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic heavy metal ions activate the heme-regulated eukaryotic initiation factor-2 alpha kinase by inhibiting the capacity of hemin-supplemented reticulocyte lysates to reduce disulfide bonds

1 reference

https://pubmed.ncbi.nlm.nih.gov/10454533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.19.9.5861

1 reference

Europe PubMed Central

30 July 2017

release_ej7fd5nqw5hvvaopvj3szmai5e

1 reference

https://api.fatcat.wiki/v0/release/ej7fd5nqw5hvvaopvj3szmai5e

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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