(Q33964721)

30 July 2017

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title

Therapeutic potential of cannabinoids in CNS disease (English)

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30 July 2017

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J Ludovic Croxford

1

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30 July 2017

1 January 2003

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30 July 2017

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30 July 2017

17

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30 July 2017

179-202

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30 July 2017

3

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https://scigraph.springernature.com/pub.10.2165/00023210-200317030-00004

30 July 2017

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cites work

The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00023210-200317030-00004

Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats

21 January 2018

1 reference

12 December 2020

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors

1 reference

12 December 2020

Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

1 reference

12 December 2020

Cannabinoids control spasticity and tremor in a multiple sclerosis model

1 reference

12 December 2020

Cannabinoid receptor localization in brain

1 reference

12 December 2020

Molecular cloning of two cannabinoid type 1-like receptor genes from the puffer fish Fugu rubripes

1 reference

12 December 2020

Ondansetron: a selective 5-HT(3) receptor antagonist and its applications in CNS-related disorders.

1 reference

12 December 2020

Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion?

1 reference

12 December 2020

In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum

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12 December 2020

Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity.

1 reference

12 December 2020

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

1 reference

12 December 2020

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

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12 December 2020

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

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12 December 2020

Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation

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12 December 2020

The development of cannabinoid antagonists.

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12 December 2020

Identification of cannabinoid receptors in cultures of rat cerebellar granule cells.

1 reference

12 December 2020

Trends in the pathophysiology and pharmacotherapy of spasticity

1 reference

12 December 2020

Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.

1 reference

12 December 2020

Pharmacology of cannabinoid CB1 and CB2 receptors.

1 reference

12 December 2020

The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons

1 reference

12 December 2020

Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry

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12 December 2020

Recent advantages in cannabinoid research

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12 December 2020

Californian centre will test medical uses of cannabis

1 reference

12 December 2020

The anandamide transport inhibitor AM404 activates vanilloid receptors.

1 reference

12 December 2020

Aminoalkylindoles: structure-activity relationships of novel cannabinoid mimetics

1 reference

12 December 2020

Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis

1 reference

12 December 2020

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells

1 reference

12 December 2020

Pharmacological evaluation of aerosolized cannabinoids in mice

1 reference

12 December 2020

Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system

1 reference

12 December 2020

Pharmacology and potential therapeutic uses of cannabis

1 reference

12 December 2020

Inhibition of serotonin release in the mouse brain via presynaptic cannabinoid CB1 receptors

1 reference

12 December 2020

SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.

1 reference

12 December 2020

Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors.

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12 December 2020

Molecular characterization of a peripheral receptor for cannabinoids

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12 December 2020

Antihyperalgesic effects of spinal cannabinoids.

1 reference

12 December 2020

Expression of a brain-type cannabinoid receptor (CB1) in alveolar Type II cells in the lung: regulation by hydrocortisone.

1 reference

12 December 2020

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

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12 December 2020

Expression of CB2 cannabinoid receptor mRNA in adult rat retina.

1 reference

12 December 2020

Adverse effects of cannabis and cannabinoids

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12 December 2020

Production and physiological actions of anandamide in the vasculature of the rat kidney.

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12 December 2020

Cannabinoid pharmacology

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12 December 2020

Dopamine activation of endogenous cannabinoid signaling in dorsal striatum

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12 December 2020

Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice

1 reference

12 December 2020

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

1 reference

12 December 2020

Antipsychotic effect of cannabidiol.

1 reference

12 December 2020

Cannabinoids inhibit excitatory neurotransmission in the substantia nigra pars reticulata

1 reference

12 December 2020

Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response.

1 reference

12 December 2020

The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain

1 reference

12 December 2020

2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice

1 reference

12 December 2020

Health consequences of acute and chronic marihuana use.

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12 December 2020

Anandamide hydrolysis by human cells in culture and brain.

1 reference

12 December 2020

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease

1 reference

12 December 2020

Comparative effects of alcohol and marijuana on mood, memory, and performance

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12 December 2020

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

1 reference

12 December 2020

Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerol

1 reference

12 December 2020

Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.

1 reference

12 December 2020

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.

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12 December 2020

Determination and characterization of a cannabinoid receptor in rat brain

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12 December 2020

Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors

1 reference

12 December 2020

Endocannabinoids control spasticity in a multiple sclerosis model

1 reference

12 December 2020

Anandamide Uptake by Human Endothelial Cells and Its Regulation by Nitric Oxide

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12 December 2020

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1 reference

12 December 2020

Recent clinical experience with dronabinol

1 reference

12 December 2020

Noxious heat activates all capsaicin-sensitive and also a sub-population of capsaicin-insensitive dorsal root ganglion neurons.

1 reference

12 December 2020

Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

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12 December 2020

Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity.

1 reference

12 December 2020

Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia

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12 December 2020

SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice.

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12 December 2020

Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves

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12 December 2020

Tetrahydrocannabinol (THC) interferes with conditioned retching in Suncus murinus: an animal model of anticipatory nausea and vomiting (ANV).

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12 December 2020

Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.

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12 December 2020

Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release.

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12 December 2020

Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals.

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12 December 2020

Glutamate excitotoxicity in a model of multiple sclerosis

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12 December 2020

A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1

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12 December 2020

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

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12 December 2020

Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain

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12 December 2020

Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.

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12 December 2020

Medical marijuana study in San Francisco: pays $1000, 25 days in hospital

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12 December 2020

Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system.

1 reference

12 December 2020

Glutamate-induced neuronal necrosis in the infant mouse hypothalamus. An electron microscopic study

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12 December 2020

The neurobiology of cannabinoid analgesia

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12 December 2020

Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats

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12 December 2020

Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures.

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12 December 2020

Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors

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12 December 2020

Cannabinoid CB1 receptor-mediated inhibition of NMDA- and kainate-stimulated noradrenaline and dopamine release in the brain

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12 December 2020

Tetrahydrocannabinol metabolism in man

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12 December 2020

The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain

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12 December 2020

Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity

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12 December 2020

Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55,212-2

1 reference

12 December 2020

Functional CB1 cannabinoid receptors in human vascular endothelial cells

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12 December 2020

Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes

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12 December 2020

Pain modulation by release of the endogenous cannabinoid anandamide

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12 December 2020

Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review

1 reference

12 December 2020

Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor

1 reference

12 December 2020

Immunohistochemical localization of the neural cannabinoid receptor in rat brain

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12 December 2020

The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

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12 December 2020

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

1 reference

12 December 2020

GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat.

1 reference

12 December 2020

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial

1 reference

12 December 2020

Leptin-regulated endocannabinoids are involved in maintaining food intake

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12 December 2020

Different effects of nabilone and cannabidiol on binocular depth inversion in Man.

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12 December 2020

Elevated endogenous cannabinoids in schizophrenia

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12 December 2020

Treatment for HIV wasting syndrome

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12 December 2020

Clinical pharmacokinetics of non-opiate abused drugs

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12 December 2020

Gi protein modulation induced by a selective inverse agonist for the peripheral cannabinoid receptor CB2: implication for intracellular signalization cross-regulation

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12 December 2020

Functional role of high-affinity anandamide transport, as revealed by selective inhibition

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12 December 2020

Evidence for a cannabinoid receptor in sea urchin sperm and its role in blockade of the acrosome reaction

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12 December 2020

Nabilone: an alternative antiemetic for cancer chemotherapy

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12 December 2020

Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.

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12 December 2020

Cannabinoid receptor CB1 mRNA is highly expressed in the rat ciliary body: implications for the antiglaucoma properties of marihuana.

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12 December 2020

The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase

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12 December 2020

Clinical Trials with Antiemetic Agents in Cancer Patients Receiving Chemotherapy

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12 December 2020

Cannabinoid CB1 receptors fail to cause relaxation, but couple via Gi/Go to the inhibition of adenylyl cyclase in carotid artery smooth muscle

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12 December 2020

Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374)

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12 December 2020

Influence of treatment of Tourette syndrome with delta9-tetrahydrocannabinol (delta9-THC) on neuropsychological performance

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12 December 2020

Antiemetic Effect of Delta-9-Tetrahydrocannabinol in Patients Receiving Cancer Chemotherapy

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12 December 2020

Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures.

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12 December 2020

Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor

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12 December 2020

Anandamide activates human platelets through a pathway independent of the arachidonate cascade

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12 December 2020

Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia

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12 December 2020

Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice

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12 December 2020

Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy

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12 December 2020

Pain relief with oral cannabinoids in familial Mediterranean fever

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12 December 2020

A second endogenous cannabinoid that modulates long-term potentiation

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12 December 2020

Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716.

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12 December 2020

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

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12 December 2020

Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus.

1 reference

12 December 2020

Adverse effects of cannabis

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12 December 2020

Cannabinoid receptors are absent in insects

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12 December 2020

Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation

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12 December 2020

Marijuana for parkinsonian tremor

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12 December 2020

A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain

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12 December 2020

Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats

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12 December 2020

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

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12 December 2020

An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing

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12 December 2020

Effects of the cannabinoid receptor antagonist SR 141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats

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12 December 2020

Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors

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12 December 2020

Review of cannabinoids and their antiemetic effectiveness.

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12 December 2020

Suppression of experimental autoimmune encephalomyelitis by cannabinoids

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12 December 2020

Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells

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12 December 2020

Therapeutic aspects of cannabis and cannabinoids

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12 December 2020

Substantia nigra: a site of action of muscle relaxant drugs.

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12 December 2020

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

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12 December 2020

Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis

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12 December 2020

Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages

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12 December 2020

Exogenous anandamide protects rat brain against acute neuronal injury in vivo.

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12 December 2020

Marihuana Smoking and Intraocular Pressure

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12 December 2020

Evaluation of intramuscular levonantradol and placebo in acute postoperative pain

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12 December 2020

Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain

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12 December 2020

Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia.

1 reference

12 December 2020

Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor

1 reference

12 December 2020

Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55,212-2.

1 reference

12 December 2020

Spinal and supraspinal components of cannabinoid-induced antinociception

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12 December 2020

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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12 December 2020

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study

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12 December 2020

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.

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12 December 2020

Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia

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12 December 2020

Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret

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12 December 2020

delta 9-Tetrahydrocannabinol, cytokines, and immunity to Legionella pneumophila

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12 December 2020

Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial

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12 December 2020

Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

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12 December 2020

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

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12 December 2020

Suppression of Cancer Chemotherapy-Induced Vomiting in the Cat by Nabilone, a Synthetic Cannabinoid

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12 December 2020

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

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12 December 2020

Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.

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12 December 2020

The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain

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12 December 2020

Gabapentin effect on spasticity in multiple sclerosis: a placebo-controlled, randomized trial

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12 December 2020

Control of pain initiation by endogenous cannabinoids.

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12 December 2020

Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage

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12 December 2020

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

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12 December 2020

Catalepsy induced by intrastriatal injections of Δ9-THC and 11-OH-Δ9-THC in the rat

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12 December 2020

Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis

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12 December 2020

Tremor-predominant Parkinson's disease. Approaches to treatment

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12 December 2020

Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.

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12 December 2020

The cannabinoid system and cytokine network

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12 December 2020

Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors

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12 December 2020

Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

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12 December 2020

The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2.

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12 December 2020

N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues.

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12 December 2020

Differential inhibition of RAW264.7 macrophage tumoricidal activity by delta 9tetrahydrocannabinol

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12 December 2020

Localization of cannabinoid CB1 receptors in the human anterior eye and retina

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12 December 2020

Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide.

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12 December 2020

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand

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12 December 2020

The perceived effects of smoked cannabis on patients with multiple sclerosis

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12 December 2020

Cannabinoid CB1 Receptor Expression in Rat Spinal Cord

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12 December 2020

Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors

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12 December 2020

Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis?

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12 December 2020

Substance use disorder and the early course of illness in schizophrenia and affective psychosis.

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12 December 2020

Neuroprotective activity of HU-211, a novel nonpsychotropic synthetic cannabinoid

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12 December 2020

Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review

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12 December 2020

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

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12 December 2020

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

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12 December 2020

The capsaicin receptor: a heat-activated ion channel in the pain pathway

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12 December 2020

Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1

1 reference

12 December 2020

Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1

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12 December 2020

Effect of dronabinol on nutritional status in HIV infection

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12 December 2020

Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma.

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12 December 2020

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

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12 December 2020

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

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12 December 2020

Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids.

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12 December 2020

Perinatal delta9-tetrahydrocannabinol exposure augmented the magnitude of motor inhibition caused by GABA(B), but not GABA(A), receptor agonists in adult rats.

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12 December 2020

Paradoxical action of the cannabinoid WIN 55,212-2 in stimulated and basal cyclic AMP accumulation in rat globus pallidus slices.

1 reference

12 December 2020

Cannabinoid receptors and immunity.

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12 December 2020

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

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12 December 2020

Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system

1 reference

12 December 2020

10.2165/00023210-200317030-00004

Identifiers

DOI

1 reference

PubMed ID

12617697

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

12617697