(Q33976656)

30 July 2017

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title

MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications (English)

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matrix-assisted laser desorption/ionization

30 July 2017

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author name string

Benjamin Balluff

1

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30 July 2017

Cedrik Schöne

2

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30 July 2017

Heinz Höfler

3

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30 July 2017

Axel Walch

4

1 reference

30 July 2017

30 July 2011

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Histochemistry and Cell Biology

30 July 2017

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30 July 2017

136

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30 July 2017

227-244

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30 July 2017

3

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https://scigraph.springernature.com/pub.10.1007/s00418-011-0843-x

30 July 2017

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21 January 2018

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Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models

21 January 2018

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21 January 2018

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Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry

21 January 2018

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Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier

21 January 2018

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Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation.

21 January 2018

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Proteomic analysis of RCL2 paraffin-embedded tissues.

21 January 2018

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Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney

21 January 2018

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Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue.

21 January 2018

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Matrix-assisted laser desorption/ionization (MALDI) mechanism revisited

21 January 2018

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Integrating histology and imaging mass spectrometry

21 January 2018

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The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.

21 January 2018

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MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue

21 January 2018

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MALDI-in source decay applied to mass spectrometry imaging: a new tool for protein identification

21 January 2018

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Normalization in MALDI-TOF imaging datasets of proteins: practical considerations

21 January 2018

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MALDI imaging combined with hierarchical clustering as a new tool for the interpretation of complex human cancers

21 January 2018

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High spatial resolution imaging mass spectrometry and classical histology on a single tissue section

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections.

21 January 2018

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Large-Scale Simultaneous Hypothesis Testing

21 January 2018

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Proteomic analysis of PAXgene-fixed tissues

21 January 2018

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A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules.

21 January 2018

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Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI imaging mass spectrometry of integral membrane proteins from ocular lens and retinal tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Citric acid antigen retrieval (CAAR) for tryptic peptide imaging directly on archived formalin-fixed paraffin-embedded tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct tissue analysis by MALDI-TOF mass spectrometry in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Sublimation as a method of matrix application for mass spectrometric imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Concise representation of mass spectrometry images by probabilistic latent semantic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Toward digital staining using imaging mass spectrometry and random forests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Protein signatures for survival and recurrence in metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Imaging mass spectrometry with silver nanoparticles reveals the distribution of fatty acids in mouse retinal sections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Comparison between vacuum sublimed matrices and conventional dried droplet preparation in MALDI-TOF mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI-MS imaging of features smaller than the size of the laser beam

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Sample preparation issues for tissue imaging by imaging MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Molecular proteomics imaging of tumor interfaces by mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Ion Formation in MALDI: The Cluster Ionization Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI-imaging mass spectrometry - An emerging technique in plant biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

A quantitative model of ultraviolet matrix-assisted laser desorption/ionization including analyte ion generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Ion formation mechanisms in UV-MALDI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

A quantitation method for mass spectrometry imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Tissue array-based predictions of pathobiology, prognosis, and response to treatment for renal cell carcinoma therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Improved MALDI-TOF imaging yields increased protein signals at high molecular mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Tag-mass: specific molecular imaging of transcriptome and proteome by mass spectrometry based on photocleavable tag.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Atmospheric pressure molecular imaging by infrared MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Ion Microprobe Mass Analyzer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Perspectives for imaging mass spectrometry in the proteomics landscape

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Liquid chromatography-tandem and MALDI imaging mass spectrometry analyses of RCL2/CS100-fixed, paraffin-embedded tissues: proteomics evaluation of an alternate fixative for biomarker discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Peptide and protein imaging mass spectrometry in cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Imaging mass spectrometry data reduction: automated feature identification and extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Automated imaging MS: Toward high throughput imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Mass spectrometry image correlation: quantifying colocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct profiling and identification of peptide expression differences in the pancreas of control and ob/ob mice by imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Massively parallel sample preparation for the MALDI MS analyses of tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct MS/MS analysis of proteins blotted on membranes by a matrix-assisted laser desorption/ionization-quadrupole ion trap-time-of-flight tandem mass spectrometer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Laser ablation electrospray ionization for atmospheric pressure molecular imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Clathrate nanostructures for mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Molecular mass spectrometry imaging in biomedical and life science research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Spatial distribution of glycerophospholipids in the ocular lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Applications of MALDI-MSI to pharmaceutical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Solvent-free matrix dry-coating for MALDI imaging of phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Approaching MALDI molecular imaging for clinical proteomic research: current state and fields of application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Protein unlocking procedures of formalin-fixed paraffin-embedded tissues: application to MALDI-TOF imaging MS investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

A review of feature selection techniques in bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Generation and detection of multiply-charged peptides and proteins by matrix-assisted laser desorption electrospray ionization (MALDESI) Fourier transform ion cyclotron resonance mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Chemical basis of the synergism and antagonism in microbial communities in the nests of leaf-cutting ants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Binary matrix for MALDI imaging mass spectrometry of phospholipids in both ion modes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time-of-flight mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Specific MALDI-MSI: Tag-Mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI imaging of formalin-fixed paraffin-embedded tissues: application to model animals of Parkinson disease for biomarker hunting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Imaging mass spectrometry for visualization of drug and endogenous metabolite distribution: toward in situ pharmacometabolomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Mass spectrometry sampling under ambient conditions with desorption electrospray ionization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Improvements of TArgeted multiplex mass spectrometry IMaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Multiplex target protein imaging in tissue sections by mass spectrometry--TAMSIM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Introduction of a 20 kHz Nd:YVO4 laser into a hybrid quadrupole time-of-flight mass spectrometer for MALDI-MS imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Automated solvent-free matrix deposition for tissue imaging by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

The modified-bead stretched sample method: development and application to MALDI-MS imaging of protein localization in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Significance analysis of microarrays applied to the ionizing radiation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

The evolving field of imaging mass spectrometry and its impact on future biological research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Lipidomics: practical aspects and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Proteomic patterns of tumour subsets in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Adapting the stretched sample method from tissue profiling to imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Mass spectrometry imaging using the stretched sample approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

MALDI mass spectrometry imaging of neuronal cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00418-011-0843-X

From whole-body sections down to cellular level, multiscale imaging of phospholipids by MALDI mass spectrometry

21 January 2018

1 reference

12 December 2020

MALDI imaging mass spectrometry in ovarian cancer for tracking, identifying, and validating biomarkers.

1 reference

12 December 2020

Ionic matrix for enhanced MALDI imaging mass spectrometry for identification of phospholipids in mouse liver and cerebellum tissue sections

1 reference

12 December 2020

Matrix sublimation/recrystallization for imaging proteins by mass spectrometry at high spatial resolution.

1 reference

12 December 2020

Revisiting rat spermatogenesis with MALDI imaging at 20-microm resolution

1 reference

12 December 2020

Imaging mass spectrometry for lipidomics

1 reference

12 December 2020

MALDI imaging and profiling MS of higher mass proteins from tissue

1 reference

12 December 2020

Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics.

1 reference

12 December 2020

Molecular imaging by mass spectrometry--looking beyond classical histology

1 reference

12 December 2020

Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI.

1 reference

12 December 2020

Identifying prostate carcinoma by MALDI-Imaging.

1 reference

12 December 2020

MALDI tissue imaging: from biomarker discovery to clinical applications.

1 reference

12 December 2020

MALDI-MS-imaging of whole human lens capsule.

1 reference

12 December 2020

MALDI mass spectrometry imaging of proteins exceeding 30,000 daltons.

1 reference

12 December 2020

Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry

1 reference

12 December 2020

Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry

1 reference

12 December 2020

10.1007/S00418-011-0843-X

Identifiers

DOI

1 reference

30 July 2017

1 reference