(Q33982884)

30 July 2017

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title

Production of recombinant protein therapeutics in cultivated mammalian cells (English)

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30 July 2017

Florian M Wurm

1

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30 July 2017

publication date

1 November 2004

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30 July 2017

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30 July 2017

volume

22

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30 July 2017

issue

11

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30 July 2017

page(s)

1393-1398

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Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells

30 July 2017

cites work

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Components of vectors for gene transfer and expression in mammalian cells

21 January 2018

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A new technique for the assay of infectivity of human adenovirus 5 DNA

21 January 2018

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Homologous plasmid recombination is elevated in immortally transformed cells

21 January 2018

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Genetic and physical linkage of exogenous sequences in transformed cells

21 January 2018

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Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects

21 January 2018

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Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.

21 January 2018

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Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing

21 January 2018

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Identification of anti-repressor elements that confer high and stable protein production in mammalian cells

21 January 2018

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Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy

21 January 2018

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Development of stable cell lines for production or regulated expression using matrix attachment regions

21 January 2018

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A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate

21 January 2018

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Gene targeting in normal and amplified cell lines

21 January 2018

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In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene

21 January 2018

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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

21 January 2018

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Effects of methotrexate on transfected DNA stability in mammalian cells

21 January 2018

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Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells.

21 January 2018

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High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker

21 January 2018

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Advances in animal cell recombinant protein production: GS-NS0 expression system

21 January 2018

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Molecular definition of predictive indicators of stable protein expression in recombinant NS0 myeloma cells

21 January 2018

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High-level expression of recombinant IgG in the human cell line per.c6.

21 January 2018

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Characterization of the stability of recombinant protein production in the GS-NS0 expression system

21 January 2018

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Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.

21 January 2018

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Large-scale transient expression in mammalian cells for recombinant protein production

21 January 2018

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Gas-inducible transgene expression in mammalian cells and mice

21 January 2018

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Kinetics of recombinant immunoglobulin production by mammalian cells in continuous culture

21 January 2018

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7 January 2021

How introns influence and enhance eukaryotic gene expression

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7 January 2021

Methods for DNA introduction into mammalian cells

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7 January 2021

Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vector

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7 January 2021

Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate

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7 January 2021

Inducible overproduction of the mouse c-myc protein in mammalian cells

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7 January 2021

Isolation of overproducing recombinant mammalian cell lines by a fast and simple selection procedure

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7 January 2021

Higher productivity of growth-arrested Chinese hamster ovary cells expressing the cyclin-dependent kinase inhibitor p27

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7 January 2021

Chromosomal Evolution in Cell Populations

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7 January 2021

Recombinant follicle stimulating hormone: development of the first biotechnology product for the treatment of infertility. Recombinant Human FSH Product Development Group

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7 January 2021

Adaptation of mammalian cells to growth in serum-free media

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7 January 2021

Laboratory scaleup of cell cultures (0.5-50 liters).

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7 January 2021

Identifiers

DOI

10.1038/NBT1026

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30 July 2017

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