(Q33989877)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

1 reference

title

Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

I Rahman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 May 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

Free Radical Biology and Medicine

9 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

1405-1420

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

Functions of glutathione and glutathione disulfide in immunology and immunopathology.

9 November 2019

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Gene expression and the thiol redox state

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7 January 2021

An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro

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Epithelial Permeability, Inflammation, and Oxidant Stress in the Air Spaces of Smokers

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Oxidants/antioxidants in idiopathic pulmonary fibrosis

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7 January 2021

Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis

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7 January 2021

Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome

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7 January 2021

Systemic deficiency of glutathione in cystic fibrosis

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7 January 2021

Glutathione depletion in epithelial lining fluid of lung allograft patients

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7 January 2021

Systemic glutathione deficiency in symptom-free HIV-seropositive individuals

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7 January 2021

Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma

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7 January 2021

Role of oxidants/antioxidants in smoking-induced lung diseases

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7 January 2021

Systemic oxidative stress in asthma, COPD, and smokers

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7 January 2021

Cytokine expression in chronic inflammatory disease

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7 January 2021

Role of transcription factors in inflammatory lung diseases

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7 January 2021

NF-kappaB as a primary regulator of the stress response

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7 January 2021

Transcription factors and asthma

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7 January 2021

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7 January 2021

Biologic and pharmacologic regulation of mammalian glutathione synthesis

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7 January 2021

Regulation of hepatic glutathione synthesis: current concepts and controversies.

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7 January 2021

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

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7 January 2021

Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma

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7 January 2021

Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells

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7 January 2021

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

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7 January 2021

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

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7 January 2021

Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1.

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7 January 2021

Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

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7 January 2021

Mechanisms of use of extracellular glutathione by lung epithelial cells and pulmonary artery endothelial cells

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7 January 2021

Ozone-induced alterations in glutathione in lung subcompartments of rats and monkeys

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7 January 2021

Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells

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7 January 2021

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

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7 January 2021

Antioxidant enzyme regulation and resistance to oxidants of human bronchial epithelial cells cultured under hyperoxic conditions

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7 January 2021

Nitric oxide-dependent induction of glutathione synthesis through increased expression of gamma-glutamylcysteine synthetase

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7 January 2021

Nitric oxide increases cellular glutathione levels in rat lung fibroblasts

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7 January 2021

The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for γ-glutamylcysteine synthetase and γ-glutamyl transpeptidase

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7 January 2021

Effect of selenium on glutathione metabolism. Induction of gamma-glutamylcysteine synthetase and glutathione reductase in the rat liver

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7 January 2021

Stimulation of glutathione synthesis in iron-loaded mice

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7 January 2021

Up-regulation of glutathione synthesis in rat kidney by methyl mercury. Relationship to mercury-induced oxidative stress

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7 January 2021

Cadmium resistance in A549 cells correlates with elevated glutathione content but not antioxidant enzymatic activities.

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7 January 2021

Expression of glutathione and gamma-glutamylcysteine synthetase mRNA is Jun dependent

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7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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7 January 2021

Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion

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7 January 2021

Regulation of human gamma-glutamylcysteine synthetase: co-ordinate induction of the catalytic and regulatory subunits in HepG2 cells

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7 January 2021

Increased gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity

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7 January 2021

Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH).

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7 January 2021

Effects of pyrrolidine dithiocarbamate on endothelial cells: protection against oxidative stress

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7 January 2021

Pyrrolidine dithiocarbamate up-regulates the expression of the genes encoding the catalytic and regulatory subunits of gamma-glutamylcysteine synthetase and increases intracellular glutathione levels

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7 January 2021

Increase in gamma-glutamylcysteine synthetase activity as a mechanism for butylated hydroxyanisole-mediated elevation of hepatic glutathione

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7 January 2021

Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines

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7 January 2021

Up-regulation of glutamate-cysteine ligase gene expression by butylated hydroxytoluene is mediated by transcription factor AP-1.

1 reference

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7 January 2021

Apocynin increases glutathione synthesis and activates AP-1 in alveolar epithelial cells

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7 January 2021

Mechanisms of action of glucocorticoids in asthma

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Cellular glutathione turnover in vitro, with emphasis on type II pneumocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Distribution of the monochlorobimane-glutathione conjugate between nucleus and cytosol in isolated hepatocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Bcl-2 expression causes redistribution of glutathione to the nucleus

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7 January 2021

Oxidative stress: role of mitochondria and protection by glutathione

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7 January 2021

Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues

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7 January 2021

Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro

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7 January 2021

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

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7 January 2021

Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases

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7 January 2021

Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis.

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7 January 2021

Mitochondrial glutathione modulates TNF-alpha-induced endothelial cell dysfunction

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7 January 2021

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

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7 January 2021

Gene transfer of mitochondrially targeted glutathione reductase protects H441 cells from t-butyl hydroperoxide-induced oxidant stresses

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7 January 2021

Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells.

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7 January 2021

Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants

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7 January 2021

Lipid peroxidation is involved in the activation of NF-kappaB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304. Lack of involvement of H2O2 in NF-kappaB activation by either cytokine in both primary and transf

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7 January 2021

Optimal NF kappa B mediated transcriptional responses in Jurkat T cells exposed to oxidative stress are dependent on intracellular glutathione and costimulatory signals

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7 January 2021

Glutathione downregulates the phosphorylation of I kappa B: autoloop regulation of the NF-kappa B-mediated expression of NF-kappa B subunits by TNF-alpha in mouse vascular endothelial cells

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7 January 2021

Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1

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7 January 2021

Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress

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7 January 2021

Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway

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7 January 2021

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

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7 January 2021

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

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7 January 2021

Role of complement, chemokines, and regulatory cytokines in acute lung injury

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7 January 2021

Redox regulation of fos and jun DNA-binding activity in vitro

1 reference

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7 January 2021

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1 reference

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7 January 2021

Redox regulation of c-Jun DNA binding by reversible S-glutathiolation.

1 reference

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7 January 2021

Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1.

1 reference

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7 January 2021

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

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7 January 2021

BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity

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7 January 2021

The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents

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7 January 2021

Regulation of JNK signaling by GSTp

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7 January 2021

Role of oxidants and antioxidants in the induction of AP-1, NF-kappaB, and glutathione S-transferase gene expression

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7 January 2021

Airway epithelial cells and mediators of inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Adhesion molecules and inflammatory injury.

1 reference

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7 January 2021

H2O2 and tumor necrosis factor-alpha induce differential binding of the redox-responsive transcription factors AP-1 and NF-kappaB to the interleukin-8 promoter in endothelial and epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Thiol regulation of the production of TNF-alpha, IL-6 and IL-8 by human alveolar macrophages

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7 January 2021

N-Acetylcysteine and glutathione as inhibitors of tumor necrosis factor production

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7 January 2021

Molecular mechanisms of neutrophil-endothelial cell adhesion induced by redox imbalance

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7 January 2021

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Modulation of ICAM-1 expression by extracellular glutathione in hyperoxia-exposed human pulmonary artery endothelial cells

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7 January 2021

Reduction-oxidation (redox) state regulation of extracellular matrix metalloproteinases and tissue inhibitors in cardiac normal and transformed fibroblast cells

1 reference

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7 January 2021

Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

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7 January 2021

Regulation of nitric oxide synthase induction by iron and glutathione in asbestos-treated human lung epithelial cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

EGF-Receptor phosphorylation and signaling are targeted by H2O2 redox stress

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7 January 2021

H2O2 induces apoptosis in bovine tracheal epithelial cells in vitro

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Thiol depletion induces apoptosis in cultured lung fibroblasts

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7 January 2021

Review: The role of glutathione in the regulation of apoptosis

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7 January 2021

Exposure to hyperoxia decreases the expression of vascular endothelial growth factor and its receptors in adult rat lungs

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione Levels Discriminate between Oxidative Stress and Transforming Growth Factor-β Signaling in Activated Rat Hepatic Stellate Cells

1 reference

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7 January 2021

Thiol modulation of TNF alpha and IL-1 induced MnSOD gene expression and activation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Protective effects of heme oxygenase-1 against oxidant-induced injury in the cultured human tracheal epithelium

1 reference

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7 January 2021

Heme oxygenase-1 gene expression by a glutathione depletor, phorone, mediated through AP-1 activation in rats

1 reference

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7 January 2021

Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene

1 reference

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7 January 2021

Attenuation by glutathione of hsp72 gene expression induced by cadmium in cisplatin-resistant human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Enzyme induction by L-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Regulation of cytochrome P4501A metabolism by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Effect of thiols on cadmium-induced expression of metallothionein and other oxidant stress genes in rat lung epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis

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7 January 2021

Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression

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https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-controlled clinical study.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Contraction of human airways by oxidative stress protection by N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Effect of the mucoactive drug nacystelyn on the respiratory burst of human blood polymorphonuclear neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione monoesters

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Modulation of endothelial GSH concentrations: effect of exogenous GSH and GSH monoethyl ester

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Radioprotection by glutathione ester: transport of glutathione ester into human lymphoid cells and fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Cellular glutathione as a determinant of sensitivity to mercuric chloride toxicity. Prevention of toxicity by giving glutathione monoester

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione monoethyl ester can selectively protect liver from high dose BCNU or cyclophosphamide

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Transport of glutathione, as gamma-glutamylcysteinylglycyl ester, into liver and kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Elevation of endogenous nucleophiles in rat lung by cysteine and glutathione esters in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Gamma-glutamylcysteinylethyl ester attenuates progression of carbon tetrachloride-induced acute liver injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

L-2-oxothiazolidine-4-carboxylate protects cultured endothelial cells against hyperoxia-induced injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione deficiency decreases tissue ascorbate levels in newborn rats: ascorbate spares glutathione and protects

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Nebulized Glutathione Induces Bronchoconstriction in Patients with Mild Asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2800%2900215-X

7 January 2021

10.1016/S0891-5849(00)00215-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10924859%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference