(Q33991251)

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Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa

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scholarly article

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2 February 2020

Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa (English)

1 reference

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2 February 2020

cystic fibrosis

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Pseudomonas aeruginosa

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transmembrane protein

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4

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2 February 2020

author name string

Julie Bérubé

1

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2 February 2020

Lucie Roussel

2

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2 February 2020

Leila Nattagh

3

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2 February 2020

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publication date

11 May 2010

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2 February 2020

Journal of Biological Chemistry

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2 February 2020

285

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2 February 2020

29

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2 February 2020

22299-22307

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2 February 2020

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

1 reference

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Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells.

1 reference

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Pyogenic bacterial infections in humans with MyD88 deficiency

1 reference

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5 July 2018

Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells

1 reference

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5 July 2018

IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

p38 MAP-kinases pathway regulation, function and role in human diseases

1 reference

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Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

1 reference

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Nod-like proteins in immunity, inflammation and disease

1 reference

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Role for erbin in bacterial activation of Nod2

1 reference

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

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5 July 2018

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts

1 reference

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How Toll-like receptors signal: what we know and what we don't know

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5 July 2018

Generation and characterization of p38beta (MAPK11) gene-targeted mice.

1 reference

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5 July 2018

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

1 reference

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5 July 2018

Airway epithelial cell tolerance to Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding

1 reference

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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

1 reference

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5 July 2018

Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

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Exacerbations: etiology and pathophysiologic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

Lung infections associated with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

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TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide.

1 reference

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5 July 2018

Oxidative stress and gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

Abnormal glutathione transport in cystic fibrosis airway epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

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Chemokine expression in CF epithelia: implications for the role of CFTR in RANTES expression

1 reference

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5 July 2018

Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903409

5 July 2018

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

1 reference

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5 July 2018

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

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5 July 2018

TRAF6 is a signal transducer for interleukin-1

1 reference

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Osmotic regulation of cytokine synthesis in vitro

1 reference

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The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor

1 reference

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Inflammatory cytokines in cystic fibrosis lungs

1 reference

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

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1 reference

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1 reference

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Immunohistopathologic localization of Pseudomonas aeruginosa in lungs from patients with cystic fibrosis. Implications for the pathogenesis of progressive lung deterioration

1 reference

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A frame-shift mutation in the cystic fibrosis gene.

1 reference

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5 July 2018

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.098566

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Cytokine secretion by cystic fibrosis airway epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.098566

21 January 2018

Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20460375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20460375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered respiratory epithelial cell cytokine production in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20460375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.098566

1 reference

Europe PubMed Central

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2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460375%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20460375%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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