(Q33997879)

30 July 2017

title

Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial (English)

1 reference

30 July 2017

main subject

phase II clinical trial

0 references

author name string

Brian I Rini

1

1 reference

30 July 2017

Bohuslav Melichar

2

1 reference

30 July 2017

Takeshi Ueda

3

1 reference

30 July 2017

Viktor Grünwald

4

1 reference

30 July 2017

Mayer N Fishman

5

1 reference

30 July 2017

José A Arranz

6

1 reference

30 July 2017

Angel H Bair

7

1 reference

30 July 2017

Yazdi K Pithavala

8

1 reference

30 July 2017

Glen I Andrews

9

1 reference

30 July 2017

Dmitri Pavlov

10

1 reference

30 July 2017

Sinil Kim

11

1 reference

30 July 2017

Eric Jonasch

12

1 reference

30 July 2017

publication date

18 October 2013

1 reference

Lancet Oncology Commission

30 July 2017

published in

1 reference

30 July 2017

volume

14

1 reference

30 July 2017

issue

12

1 reference

30 July 2017

page(s)

1233-1242

1 reference

Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial

30 July 2017

cites work

1 reference

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5 July 2018

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Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial

5 July 2018

1 reference

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Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis

5 July 2018

1 reference

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Antiangiogenic therapy for advanced renal cell carcinoma: management of treatment-related toxicities

5 July 2018

1 reference

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5 July 2018

1 reference

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Key predictive factors of axitinib (AG-013736)-induced proteinuria and efficacy: a phase II study in Japanese patients with cytokine-refractory metastatic renal cell Carcinoma

5 July 2018

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Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib

5 July 2018

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Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial

5 July 2018

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Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study

5 July 2018

1 reference

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Randomized phase II designs.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

Novel designs and end points for phase II clinical trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

5 July 2018

1 reference

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Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206

5 July 2018

1 reference

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Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

5 July 2018

1 reference

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Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study

5 July 2018

1 reference

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Sorafenib in advanced clear-cell renal-cell carcinoma

5 July 2018

1 reference

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

5 July 2018

1 reference

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Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results

5 July 2018

1 reference

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CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment

5 July 2018

1 reference

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

5 July 2018

1 reference

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Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

Randomized phase II trial of first-line treatment with sorafenib versus interferon Alfa-2a in patients with metastatic renal cell carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120767

A Phase I study to evaluate the pharmacokinetics of axitinib (AG-13736) in healthy Chinese volunteers

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970464-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970464-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S1470-2045(13)70464-9

1 reference

30 July 2017

1 reference

30 July 2017

1 reference