(Q34001959)

30 July 2017

1 reference

title

KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy (English)

1 reference

30 July 2017

Rogawski MA

1

1 reference

PubMed ID

10941184

30 July 2017

language of work or name

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1 September 2000

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30 July 2017

Trends in Neurosciences

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30 July 2017

23

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30 July 2017

9

1 reference

30 July 2017

393-398

1 reference

Benign familial neonatal convulsions linked to genetic markers on chromosome 20.

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

A potassium channel mutation in neonatal human epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

The KCNQ2 potassium channel: splice variants, functional and developmental expression. Brain localization and comparison with KCNQ3

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

1 reference

7 January 2021

Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Susceptibility genes in human epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Long QT syndromes and torsade de pointes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Voltage-gated ion channels and hereditary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Episodic ataxia mutations in Kv1.1 alter potassium channel function by dominant negative effects or haploinsufficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Deletion of the K(V)1.1 potassium channel causes epilepsy in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Developmental seizure susceptibility of kv1.1 potassium channel knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

The LQT syndromes--current status of molecular mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Taking the "idio" out of "idiosyncratic": predicting torsades de pointes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Novel KCNQ1 and HERG missense mutations in Dutch long-QT families

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

C-terminal HERG mutations: the role of hypokalemia and a KCNQ1-associated mutation in cardiac event occurrence

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Alternative mechanism for pathogenesis of an inherited epilepsy by a nicotinic AChR mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Generalized epilepsy with febrile seizures plus: A common childhood-onset genetic epilepsy syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Treatment of myotonia with antiarrhythmic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Pharmacological targeting of long QT mutant sodium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Improvement of repolarization abnormalities by a K+ channel opener in the LQT1 form of congenital long-QT syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Genetically defined therapy of inherited long-QT syndrome. Correction of abnormal repolarization by potassium

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

The anticonvulsant retigabine potently suppresses epileptiform discharges in the low Ca ++ and low Mg++ model in the hippocampal slice preparation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Effects of retigabine (D-23129) on different patterns of epileptiform activity induced by low magnesium in rat entorhinal cortex hippocampal slices.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Characterization of the K+ channel opening effect of the anticonvulsant retigabine in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901629-5

7 January 2021

10.1016/S0166-2236(00)01629-5

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10941184