(Q34005315)

30 July 2017

title

Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells (English)

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30 July 2017

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Jie Zheng

1

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30 July 2017

Alice Hudder

series ordinal

2

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30 July 2017

Kim Zukowski

series ordinal

3

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30 July 2017

Raymond F Novak

series ordinal

4

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30 July 2017

language of work or name

English

0 references

publication date

22 April 2010

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30 July 2017

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30 July 2017

volume

296

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30 July 2017

issue

1

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30 July 2017

page(s)

74-87

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Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

30 July 2017

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5 July 2018

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Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition

5 July 2018

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Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograft lesions: biomarkers of progression

5 July 2018

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5 July 2018

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Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer

5 July 2018

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Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors

5 July 2018

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Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

5 July 2018

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Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts

5 July 2018

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

5 July 2018

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Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer

5 July 2018

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5 July 2018

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Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer

5 July 2018

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5 July 2018

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Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function

5 July 2018

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5 July 2018

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Xenograft models of premalignant breast disease

5 July 2018

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Determinants of rapamycin sensitivity in breast cancer cells

5 July 2018

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5 July 2018

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Mammalian target of rapamycin: a new molecular target for breast cancer

5 July 2018

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Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells

5 July 2018

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Transformation of human breast epithelial cells by c-Ha-ras oncogene

5 July 2018

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Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

5 July 2018

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Morphological expression of cell transformation induced by c-Ha-ras oncogene in human breast epithelial cells

5 July 2018

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TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.

5 July 2018

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29 October 2018

mTOR-what does it do?

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Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

29 October 2018

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The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

29 October 2018

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Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells

29 October 2018

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Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906627

mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer

29 October 2018

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Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.

29 October 2018

1 reference

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Progression of premalignant MCF10AT generates heterogeneous malignant variants with characteristic histologic types and immunohistochemical markers.

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20417028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CANLET.2010.03.018

1 reference

30 July 2017

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30 July 2017

1 reference