(Q34006052)

30 July 2017

title

Immunomodulatory effects of anti-CD4 antibody in host resistance against infections and tumors in human CD4 transgenic mice (English)

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30 July 2017

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D J Herzyk

1

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30 July 2017

E R Gore

2

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30 July 2017

R Polsky

3

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30 July 2017

K L Nadwodny

4

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30 July 2017

C C Maier

5

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30 July 2017

S Liu

6

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30 July 2017

T K Hart

7

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30 July 2017

A G Harmsen

8

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30 July 2017

P J Bugelski

9

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30 July 2017

language of work or name

English

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publication date

1 February 2001

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30 July 2017

published in

Infection and Immunity

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30 July 2017

volume

69

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30 July 2017

issue

2

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30 July 2017

page(s)

1032-1043

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Immune-mediated inflammation directly impairs pulmonary function, contributing to the pathogenesis of Pneumocystis carinii pneumonia

30 July 2017

cites work

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Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo.

5 July 2018

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A primatized MAb to human CD4 causes receptor modulation, without marked reduction in CD4+ T cells in chimpanzees: in vitro and in vivo characterization of a MAb (IDEC-CE9.1) to human CD4.

5 July 2018

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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans

5 July 2018

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A novel method for real time quantitative RT-PCR.

5 July 2018

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Real time quantitative PCR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Production and function of cytokines in natural and acquired immunity to Candida albicans infection

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.

5 July 2018

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Phase 1 clinical trial of chimeric monoclonal anti-CD4 antibody in multiple sclerosis

5 July 2018

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Anti-CD4 therapy in recent-onset IDDM.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Circulating CD4 and CD8 T cells have little impact on host defense against experimental vaginal candidiasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Active immunity to Pneumocystis carinii reinfection in T-cell-depleted mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

The pathogenesis of acute systemic candidiasis in a susceptible inbred mouse strain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Cellular and humoral immunity to Leishmania major in genetically susceptible mice after in vivo depletion of L3T4+ T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

CD4+ helper T cells are required for resistance to a highly metastatic murine tumor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Interaction between CD4 and class II MHC molecules mediates cell adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Role of L3T4+ lymphocytes in protective immunity to systemic Candida albicans infection in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Susceptibility of beige mutant mice to candidiasis may be linked to a defect in granulocyte production by bone marrow stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Tumor necrosis factor and interleukin-6 in Candida albicans infection in normal and granulocytopenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Altered IFN-gamma and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Clinical and immunologic effects of a PRIMATIZED anti-CD4 monoclonal antibody in active rheumatoid arthritis: results of a phase I, single dose, dose escalating trial.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Anti-β1Integrin IgG Inhibits Pulmonary Macrometastasis and the Size of Micrometastases from a Murine Mammary Carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Specific suppression of responses to Leishmania tropica by a cloned T-cell line

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

An enzyme-linked immunosorbent assay for quantifying adherence of Candida to human vascular endothelium

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=97984

Comparative pharmacodynamics of keliximab and clenoliximab in transgenic mice bearing human CD4

29 October 2018

1 reference

12 December 2020

Cell adhesion and experimental metastasis: a study using the B16 malignant melanoma model system

1 reference

12 December 2020

Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker

1 reference

12 December 2020

Innate and acquired immune responses against Candida albicans in congenic B10.D2 mice with deficiency of the C5 complement component

1 reference

12 December 2020

Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells

1 reference

12 December 2020

Suppression of the humoral response to anti-CD3 mAB by pretreatment with anti-CD4 mAB

1 reference

12 December 2020

Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major

1 reference

12 December 2020

Role of natural killer and T-cells in interferon induced inhibition of spontaneous metastases of the B16F10L murine melanoma

1 reference

12 December 2020

Suppression of the immune response to immunotoxins with anti-CD4 monoclonal antibodies

1 reference

12 December 2020

Single-organism model of host defense against infection: a novel immunotoxicologic approach to evaluate immunomodulatory drugs

1 reference

12 December 2020

Treatment of a newly established transgenic model of chronic arthritis with nondepleting anti-CD4 monoclonal antibody

1 reference

12 December 2020

Immunocytokines: a promising approach to cancer immunotherapy

1 reference

12 December 2020

Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors

1 reference

12 December 2020

Humanised monoclonal antibody therapy for rheumatoid arthritis

1 reference

12 December 2020

In vivo inhibition by a monoclonal antibody to CD4+ T cells of humoral and cellular immunity in sheep

1 reference

12 December 2020

Control of immune-mediated disease of the central nervous system with monoclonal (CD4-specific) antibodies

1 reference

12 December 2020

Strain dependence of antibody-mediated protection in murine systemic candidiasis

1 reference

12 December 2020

Age influences recovery of systemic and mucosal immune responses following acute depletion of CD4 T cells

1 reference

12 December 2020

Elimination of CD4+ T cells in mice bearing an advanced sarcoma augments the antitumor action of interleukin-2

1 reference

12 December 2020

Efficacy of tumor-infiltrating lymphocytes in the treatment of hepatic metastases arising from transgenic intraocular tumors in mice

1 reference

12 December 2020

Inhibition of contact sensitivity in human CD4+ transgenic mice by human CD4-specific monoclonal antibodies: CD4+ T-cell depletion is not required

1 reference

12 December 2020

10.1128/IAI.69.2.1032-1043.2001

Identifiers

DOI

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30 July 2017

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30 July 2017

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