(Q34006206)

30 July 2017

title

Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins (English)

1 reference

30 July 2017

main subject

Clostridium difficile

0 references

author name string

A Nusrat

1

1 reference

30 July 2017

C von Eichel-Streiber

2

1 reference

30 July 2017

J R Turner

3

1 reference

30 July 2017

P Verkade

4

1 reference

30 July 2017

J L Madara

5

1 reference

30 July 2017

C A Parkos

6

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 March 2001

1 reference

30 July 2017

published in

Infection and Immunity

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30 July 2017

volume

69

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30 July 2017

issue

3

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30 July 2017

page(s)

1329-1336

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Tight junctions are membrane microdomains

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

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5 July 2018

1 reference

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The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

5 July 2018

1 reference

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A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts

5 July 2018

1 reference

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Microdomains of GPI-anchored proteins in living cells revealed by crosslinking

5 July 2018

1 reference

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GPI-anchored proteins are organized in submicron domains at the cell surface.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

5 July 2018

1 reference

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Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

5 July 2018

1 reference

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Clostridium difficile toxins A and B are cation-dependent UDP-glucose hydrolases with differing catalytic activities

5 July 2018

1 reference

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Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia

5 July 2018

1 reference

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Rho GTPases and the actin cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Phosphorylation of occludin correlates with occludin localization and function at the tight junction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes?

5 July 2018

1 reference

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Toxins A and B from Clostridium difficile differ with respect to enzymatic potencies, cellular substrate specificities, and surface binding to cultured cells

5 July 2018

1 reference

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Mammalian occludin in epithelial cells: its expression and subcellular distribution

5 July 2018

1 reference

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Functional rafts in cell membranes

5 July 2018

1 reference

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5 July 2018

1 reference

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Large clostridial cytotoxins--a family of glycosyltransferases modifying small GTP-binding proteins

5 July 2018

1 reference

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Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Isolation of plasma membrane fractions from the intestinal epithelial model T84.

5 July 2018

1 reference

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Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

5 July 2018

1 reference

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Occludin: a novel integral membrane protein localizing at tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Caveolae: where incoming and outgoing messengers meet

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and inducti

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Expression and polarized targeting of a rab3 isoform in epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Clostridium difficile toxin B acts on the GTP-binding protein Rho.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Intestinal absorptive cell tight junctions are linked to cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structure, biochemistry, and assembly of epithelial tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Tight junction dynamics: is paracellular transport regulated?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Functional coupling of tight junctions and microfilaments in T84 monolayers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

The epithelial tight junction: structure, function and preliminary biochemical characterization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Purification of two high molecular weight toxins of Clostridium difficile which are antigenically related

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Stabilization of F-actin prevents cAMP-elicited Cl- secretion in T84 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structure, function, and regulation of cellular tight junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structure, regulation, and pathophysiology of tight junctions in the gastrointestinal tract

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Structural analysis of a human intestinal epithelial cell line.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=98024

Clostridium difficile toxin B disrupts the barrier function of T84 monolayers

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11179295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Separation of caveolae from associated microdomains of GPI-anchored proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11179295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/IAI.69.3.1329-1336.2001

1 reference

30 July 2017

1 reference

30 July 2017

1 reference