(Q34010567)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

Jihong Bai

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Ping Wang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

22 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

page(s)

1665-1670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis.

6 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

How does calcium trigger neurotransmitter release?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Synaptotagmin I functions as a calcium regulator of release probability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Initial sequencing and analysis of the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

The C2B domain of synaptotagmin is a Ca(2+)-sensing module essential for exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Calcium triggers an intramolecular association of the C2 domains in synaptotagmin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

The C2 domain calcium-binding motif: structural and functional diversity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

C2 domain conformational changes in phospholipase C-delta 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Synaptotagmin III is a novel isoform of rat synaptotagmin expressed in endocrine and neuronal cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Calcium dependence of the rate of exocytosis in a synaptic terminal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

The exocytotic fusion pore and neurotransmitter release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Synaptotagmin: a calcium sensor on the synaptic vesicle surface.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.032541099

Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.032541099

Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.032541099

Synaptic function modulated by changes in the ratio of synaptotagmin I and IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.032541099

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.032541099

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122248

Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes

29 October 2018

1 reference

12 December 2020

Calcium sensitivity of glutamate release in a calyx-type terminal

1 reference

12 December 2020

Membrane-embedded synaptotagmin penetrates cis or trans target membranes and clusters via a novel mechanism

1 reference

12 December 2020

Intracellular calcium dependence of transmitter release rates at a fast central synapse

1 reference

12 December 2020

synaptotagmin mutants reveal essential functions for the C2B domain in Ca2+-triggered fusion and recycling of synaptic vesicles in vivo

1 reference

12 December 2020

Synthesis and characterization of two fluorescent sulfhydryl reagents

1 reference

12 December 2020

Fluorescence studies of the secondary structure and orientation of a model ion channel peptide in phospholipid vesicles

1 reference

12 December 2020

Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I

1 reference

12 December 2020

Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.032541099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

0 references

release_ubrgjrmyljhmhawmojgksf4kga

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ubrgjrmyljhmhawmojgksf4kga

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11805296%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference