(Q34012771)

English

Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic (English)

1 reference

Europe PubMed Central

30 July 2017

author name string

Francis M Hughes

1

1 reference

Europe PubMed Central

30 July 2017

Brooke E Shaner

2

1 reference

Europe PubMed Central

30 July 2017

Lisa A May

3

1 reference

Europe PubMed Central

30 July 2017

Lyndsay Zotian

4

1 reference

Europe PubMed Central

30 July 2017

Justin O Brower

5

1 reference

Europe PubMed Central

30 July 2017

R Jeremy Woods

6

1 reference

Europe PubMed Central

30 July 2017

Michael Cash

7

1 reference

Europe PubMed Central

30 July 2017

Dustin Morrow

8

1 reference

Europe PubMed Central

30 July 2017

Fabienne Massa

9

1 reference

Europe PubMed Central

30 July 2017

Jean Mazella

10

1 reference

Europe PubMed Central

30 July 2017

Thomas A Dix

11

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

1 June 2010

1 reference

Europe PubMed Central

30 July 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

30 July 2017

53

1 reference

Europe PubMed Central

30 July 2017

12

1 reference

Europe PubMed Central

30 July 2017

4623-4632

1 reference

Europe PubMed Central

30 July 2017

Cancer, chemistry, and the cell: molecules that interact with the neurotensin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Neurotensin and pain modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

FE200041 (D-Phe-D-Phe-D-Nle-D-Arg-NH2): A peripheral efficacious kappa opioid agonist with unprecedented selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

A single amino acid of the human and rat neurotensin receptors (subtype 1) determining the pharmacological profile of a species-selective neurotensin agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Stable expression of the cloned rat brain neurotensin receptor into fibroblasts: binding properties, photoaffinity labeling, transduction mechanisms, and internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Quantitative assessment of tactile allodynia in the rat paw

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

A pharmacological profile of the novel, peripherally-selective kappa-opioid receptor agonist, EMD 61753.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Pharmacological and biochemical profiles of unique neurotensin 8-13 analogs exhibiting species selectivity, stereoselectivity, and superagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Centrally administered neurotensin suppresses locomotor hyperactivity induced by d-amphetamine but not by scopolamine or caffeine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Opioid agonists and antagonists: an evaluation of their peripheral actions in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Alterations in nociception and body temperature after intracisternal administration of neurotensin, beta-endorphin, other endogenous peptides, and morphine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Neurotensin administered intracisternally inhibits responsiveness of mice to noxious stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

5 July 2018

Potentiation by thiorphan and bestatin of the naloxone-insensitive analgesic effects of neurotensin and neuromedin n.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Antinociceptive activity of the methanolic extract of Kaempferia galanga Linn. in experimental animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Cellular uptake of a radiolabelled analogue of neurotensin in the Caco-2 cell model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

In vivo behavioral effects of stable, receptor-selective neurotensin[8-13] analogues that cross the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood–brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Targeted inactivation of the neurotensin type 1 receptor reveals its role in body temperature control and feeding behavior but not in analgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Selectivity enhancement induced by substitution of non-natural analogues of arginine and lysine in arginine-based thrombin inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Improved solid-phase peptide synthesis method utilizing alpha-azide-protected amino acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Identification of the receptor subtype involved in the analgesic effect of neurotensin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Evidence for additional neurotensin receptor subtypes: neurotensin analogs that distinguish between neurotensin-mediated hypothermia and antinociception.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908295

29 October 2018

Nifedipine-induced analgesia after epidural injection in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociated effects of inhibitors of enkephalin-metabolising peptidases or naloxone on various nociceptive responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design rationale, synthesis, and characterization of non-natural analogs of the cationic amino acids arginine and lysine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-nociceptive activity of the aqueous extract of Erythrina velutina leaves

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modified receptacle method for animal analgesimetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of novel hexapeptides with neurotensin activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotensin binding to extraneural and neural receptors: comparison with biological activity and structure--activity relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotensin: perchance an endogenous neuroleptic?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly potent neurotensin analog that causes hypothermia and antinociception

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the cardiovascular effects of neurotensin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20481538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM100092S

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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