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The aging process: where are the drug opportunities?
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The aging process: where are the drug opportunities?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
author name string
Smith RG
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 August 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
published in
Current Opinion in Chemical Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
volume
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
page(s)
371-376
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
cites work
Peptidomimetic regulation of growth hormone secretion
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Crossref
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A New Orphan Receptor Involved in Pulsatile Growth Hormone Release.
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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A receptor in pituitary and hypothalamus that functions in growth hormone release
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Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from Pufferfish to humans
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects
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Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in man
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Oral administration of the growth hormone secretagogue MK-677 increases markers of bone turnover in healthy and functionally impaired elderly adults. The MK-677 Study Group
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Hexarelin, a growth hormone - releasing peptide, counteracts bone loss in gonadectomized male rats
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Effect of recombinant human growth hormone in elderly osteoporotic women
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Impaired cardiac performance in elderly patients with growth hormone deficiency.
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Crossref
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Growth hormone and hexarelin prevent endothelial vasodilator dysfunction in aortic rings of the hypophysectomized rat
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Cardiac effects of hexarelin in hypopituitary adults
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Identification and characterization of a new growth hormone-releasing peptide receptor in the heart
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
1 reference
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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
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Cellular mechanisms of beta-amyloid production and secretion
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7 January 2021
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Purification and cloning of amyloid precursor protein beta-secretase from human brain
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Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Neuroendocrine influences and repercussions of the menopause
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Alternatives to the use of estrogen in postmenopausal women
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Estrogen actions in the central nervous system
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Estrogen is more than just a "sex hormone": novel sites for estrogen action in the hippocampus and cerebral cortex
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Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Characterization of the 5'-flanking region of the human dopamine transporter gene
1 reference
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Crossref
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Smartbombs and cloaking devices
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Nuclear receptor coregulators: cellular and molecular biology
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Activity of the Nurr1 Carboxyl-terminal Domain Depends on Cell Type and Integrity of the Activation Function 2
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Lack of protection of monoamine oxidase B-deficient mice from age-related spatial learning deficits in the Morris water maze
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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l-Deprenyl, blocking apoptosis and regulating gene expression in cultured retinal neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Symptomatic and neuroprotective properties of the aliphatic propargylamines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Q64797278
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
based on heuristic
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Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1367-5931%2800%2900104-6
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7 January 2021
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Identifiers
DOI
10.1016/S1367-5931(00)00104-6
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
PubMed ID
10959763
1 reference
stated in
Europe PubMed Central
PubMed ID
10959763
retrieved
30 July 2017
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