(Q34015788)

30 July 2017

title

Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences (English)

1 reference

alternative mRNA splicing, via spliceosome

30 July 2017

0 references

1 reference

Yi Xing

1

1 reference

30 July 2017

Christopher Lee

series ordinal

2

1 reference

30 July 2017

language of work or name

English

0 references

publication date

12 September 2005

1 reference

30 July 2017

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

30 July 2017

volume

102

1 reference

30 July 2017

issue

38

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30 July 2017

page(s)

13526-13531

1 reference

Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

A combinatorial code for splicing silencing: UAGG and GGGG motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

The splicing regulatory element, UGCAUG, is phylogenetically and spatially conserved in introns that flank tissue-specific alternative exons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Systematic identification and analysis of exonic splicing silencers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

A computational and experimental approach toward a priori identification of alternatively spliced exons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Single nucleotide polymorphism-based validation of exonic splicing enhancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

A non-EST-based method for exon-skipping prediction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Computational comparative analyses of alternative splicing regulation using full-length cDNA of various eukaryotes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

The evolving roles of alternative splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Ultraconserved Elements in the Human Genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Positive selection detection in 40,000 human immunodeficiency virus (HIV) type 1 sequences automatically identifies drug resistance and positive fitness mutations in HIV protease and reverse transcriptase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Transcriptome and genome conservation of alternative splicing events in humans and mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

How prevalent is functional alternative splicing in the human genome?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Database resources of the National Center for Biotechnology Information: update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

MHC studies in nonmodel vertebrates: what have we learned about natural selection in 15 years?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Alternative splicing and evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Intronic sequences flanking alternatively spliced exons are conserved between human and mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

ETOPE: Evolutionary test of predicted exons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Conservation of human alternative splice events in mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Selecting for functional alternative splices in ESTs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

The origin and evolution of model organisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

The Ka/Ks ratio: diagnosing the form of sequence evolution

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

5 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Alu-containing exons are alternatively spliced

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Common exon duplication in animals and its role in alternative splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Listening to silence and understanding nonsense: exonic mutations that affect splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

A genomic view of alternative splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Alternative splicing and genome complexity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

The contribution of exon-skipping events on chromosome 22 to protein coding diversity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Genome-wide detection of alternative splicing in expressed sequences of human genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Statistical methods for detecting molecular adaptation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

EMBOSS: the European Molecular Biology Open Software Suite

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Frequent alternative splicing of human genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Pieces of the puzzle: expressed sequence tags and the catalog of human genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

PAML: a program package for phylogenetic analysis by maximum likelihood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

DNA sequence evolution: the sounds of silence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Unbiased estimation of the rates of synonymous and nonsynonymous substitution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Basic local alignment search tool

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

EST comparison indicates 38% of human mRNAs contain possible alternative splice forms.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Alternative splicing mechanisms for the modulation of protein function: conservation between human and other species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Origin of alternative splicing by tandem exon duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Negative selection pressure against premature protein truncation is reduced by alternative splicing and diploidy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Evolutionary Dynamics of Oncogenes and Tumor Suppressor Genes: Higher Intensities of Purifying Selection than Other Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501213102

Mammalian housekeeping genes evolve more slowly than tissue-specific genes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224612

Purifying selection on silent sites -- a constraint from splicing regulation?

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16157889

12 December 2020

inferred from PubMed ID database lookup

Estimating rates of alternative splicing in mammals and invertebrates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16157889

12 December 2020

inferred from PubMed ID database lookup

Evidence for purifying selection acting on silent sites in BRCA1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16157889

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0501213102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference