(Q34015981)

30 July 2017

Identification of a molecular activator for insulin receptor with potent anti-diabetic effects. (English)

1 reference

30 July 2017

1 reference

Kunyan He

1

1 reference

30 July 2017

Chi-Bun Chan

2

1 reference

30 July 2017

Xia Liu

3

1 reference

30 July 2017

Yonghui Jia

4

1 reference

30 July 2017

Hongbo R Luo

5

1 reference

30 July 2017

Stefan A France

6

1 reference

30 July 2017

Yang Liu

7

1 reference

30 July 2017

W David Wilson

8

1 reference

30 July 2017

Keqiang Ye

9

1 reference

30 July 2017

language of work or name

English

0 references

publication date

9 September 2011

1 reference

Journal of Biological Chemistry

30 July 2017

1 reference

30 July 2017

286

1 reference

30 July 2017

43

1 reference

30 July 2017

37379-37388

1 reference

Type 2 diabetes: where we are today: an overview of disease burden, current treatments, and treatment strategies

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Management of type 2 diabetes: oral agents, insulin, and injectables

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Naphthoquinones and their pharmacological properties

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Identification of novel orally available small molecule insulin mimetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Synthesis and evaluation of antitumor activity of novel 1,4-naphthoquinone derivatives (IV).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Selective small molecule peptidomimetic ligands of TrkC and TrkA receptors afford discrete or complete neurotrophic activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Positive and Negative Roles of p85α and p85β Regulatory Subunits of Phosphoinositide 3-Kinase in Insulin Signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Regulation of insulin receptor function by a small molecule insulin receptor activator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

In vitro cytotoxicity of 1,4-naphthoquinone derivatives to replicating cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Quinones as mutagens, carcinogens, and anticancer agents: introduction and overview.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199485

The non-peptidyl fungal metabolite L-783,281 activates TRK neurotrophin receptors

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.247387

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.247387

Plumbagin: A study of its anticancer, antibacterial & antifungal properties

21 January 2018

1 reference

12 December 2020

Effect of eicosapentaenoic and docosahexaenoic acid on natural killer cell activity in human peripheral blood lymphocytes

1 reference

12 December 2020

Radiosensitizing effect of plumbagin on mouse melanoma cells grown in vitro

1 reference

12 December 2020

Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

1 reference

12 December 2020

Mechanistic investigation on binding interaction of bioactive imidazole with protein bovine serum albumin--a biophysical study

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.247387

1 reference

release_lpsrvq57wbcffaib4yeuujejsm

30 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lpsrvq57wbcffaib4yeuujejsm

24 November 2022

mapped directly with Wikidata item

PMCID

3199485

1 reference

30 July 2017

1 reference