(Q34017913)

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Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.

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scholarly article

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18 October 2019

Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8744306%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

cystic fibrosis

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transmembrane protein

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Myles H. Akabas

2

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18 October 2019

author name string

M Cheung

1

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18 October 2019

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publication date

1 June 1996

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18 October 2019

Biophysical Journal

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18 October 2019

70

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18 October 2019

2688-2695

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18 October 2019

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8744306%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Use of site-directed fluorescence labeling to study proximity relationships in the lactose permease of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Structural basis for sugar translocation through maltoporin channels at 3.1 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Functional roles of the nucleotide-binding folds in the activation of the cystic fibrosis transmembrane conductance regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Functionally distinct phospho-forms underlie incremental activation of protein kinase-regulated Cl- conductance in mammalian heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by specific protein kinases and protein phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Generation, translocation, and presentation of MHC class I-restricted peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Regulation of CFTR Cl- channel gating by ADP and ATP analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Pore loops: an emerging theme in ion channel structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Novel pore-lining residues in CFTR that govern permeation and open-channel block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Molecular Architecture and Electrostatic Properties of a Bacterial Porin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Nucleoside triphosphates are required to open the CFTR chloride channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Expression and characterization of the cystic fibrosis transmembrane conductance regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Traffic ATPases: a superfamily of transport proteins operating from Escherichia coli to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Crystal structures explain functional properties of two E. coli porins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Mutations and sequence variations detected in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: A report from the cystic fibrosis genetic analysis consortium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

A Multifunctional Aqueous Channel Formed by CFTR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

28 July 2018

Side-chain accessibilities in the pore of a K+ channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

K+ pore structure revealed by reporter cysteines at inner and outer surfaces.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Silver as a probe of pore-forming residues in a potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Identification of 12 novel mutations in the CFTR gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Mapping of cystic fibrosis transmembrane conductance regulator membrane topology by glycosylation site insertion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane conductance regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Genotype analysis of adult cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1225248

29 October 2018

Multi-ion pore behaviour in the CFTR chloride channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two novel mutations in the transmembrane domains of the CFTR gene in subjects of Sardinian descent

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of 14 cystic fibrosis mutations in five South European populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a translocated protein segment in a voltage-dependent channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-dependent protein kinase-mediated phosphorylation of cystic fibrosis transmembrane conductance regulator residue Ser-753 and its role in channel activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8744306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0006-3495(96)79838-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8744306%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8744306%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8744306%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

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