(Q34020456)

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Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells

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Europe PubMed Central

PubMed publication ID

30 July 2017

Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Alberto Martínez

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Chandima S K Rajapakse

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Roberto A Sánchez-Delgado

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

Armando Varela-Ramirez

4

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Europe PubMed Central

PubMed publication ID

30 July 2017

Carolina Lema

5

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Europe PubMed Central

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30 July 2017

Renato J Aguilera

6

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Europe PubMed Central

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30 July 2017

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15 May 2010

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Europe PubMed Central

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30 July 2017

Journal of Inorganic Biochemistry

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Europe PubMed Central

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30 July 2017

104

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Europe PubMed Central

PubMed publication ID

30 July 2017

9

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Europe PubMed Central

PubMed publication ID

30 July 2017

967-977

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Europe PubMed Central

PubMed publication ID

30 July 2017

Water Soluble Phosphane-Gold(I) Complexes. Applications as Recyclable Catalysts in a Three-component Coupling Reaction and as Antimicrobial and Anticancer Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910123

5 July 2018

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies

1 reference

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The antimalarial activity of Ru-chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near water/n-octanol interfaces

1 reference

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5 July 2018

Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine

1 reference

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KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

1 reference

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5 July 2018

The mechanism of antimalarial action of the ruthenium(II)-chloroquine complex [RuCl(2)(CQ)] (2).

1 reference

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Antitumour metal compounds: more than theme and variations

1 reference

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Antimalarial therapy prevents Myc-induced lymphoma

1 reference

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Phenylazo-pyridine and phenylazo-pyrazole chlorido ruthenium(II) arene complexes: arene loss, aquation, and cancer cell cytotoxicity

1 reference

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Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.

1 reference

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Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.

1 reference

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Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis

1 reference

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Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)].

1 reference

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Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine.

1 reference

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5 July 2018

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

1 reference

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5 July 2018

Competitive reactions of a ruthenium arene anticancer complex with histidine, cytochrome c and an oligonucleotide

1 reference

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5 July 2018

Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers

1 reference

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5 July 2018

Cisplatin and platinum drugs at the molecular level. (Review)

1 reference

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SPECTROPHOTOMETRIC STUDIES OF THE INTERACTION OF CHLOROQUINE WITH DEOXYRIBONUCLEIC ACID

1 reference

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Pharmacokinetics of satraplatin (JM216), an oral platinum (IV) complex under daily oral administration for 5 or 14 days.

1 reference

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5 July 2018

Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910123

5 July 2018

Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

1 reference

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5 July 2018

In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

1 reference

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5 July 2018

Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A.

1 reference

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The economic and social burden of malaria

1 reference

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5 July 2018

Inhibition of cancer cell growth by ruthenium(II) arene complexes

1 reference

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5 July 2018

Current status of the development of trans-platinum antitumor drugs

1 reference

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5 July 2018

DNA as a possible target for antitumor ruthenium(III) complexes

1 reference

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5 July 2018

In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.

1 reference

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5 July 2018

Anti-proliferative activity and mechanism of action of titanocene dichloride

1 reference

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5 July 2018

Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex

1 reference

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5 July 2018

pH-dependent regulation of camptothecin-induced cytotoxicity and cleavable complex formation by the antimalarial agent chloroquine

1 reference

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5 July 2018

Major DNA fragmentation is a late event in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910123

5 July 2018

Toward a novel metal-based chemotherapy against tropical diseases. 2. Synthesis and antimalarial activity in vitro and in vivo of new ruthenium- and rhodium-chloroquine complexes

1 reference

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Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

1 reference

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5 July 2018

Toward a novel metal-based chemotherapy against tropical diseases. 1. Enhancement of the efficacy of clotrimazole against Trypanosoma cruzi by complexation to ruthenium in RuCl2(clotrimazole)2.

1 reference

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5 July 2018

Differential binding of the enantiomers of chloroquine and quinacrine to polynucleotides: implications for stereoselective metabolism

1 reference

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Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines.

1 reference

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5 July 2018

DNA: Reaction with Chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910123

5 July 2018

Reactions of quinine, chloroquine, and quinacrine with DNA and their effects on the DNA and RNA polymerase reactions

1 reference

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5 July 2018

Inhibition of DNA and RNA polymerase reactions by chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910123

5 July 2018

Studies on modes of action of chloroquine, quinacrine, and quinine and on chloroquine resistance

1 reference

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5 July 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

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Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

1 reference

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1 reference

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5 July 2018

B----Z DNA conformational changes induced by a family of dinuclear bis(platinum) complexes

1 reference

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5 July 2018

Interaction of acridine drugs with DNA and nucleotides

1 reference

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5 July 2018

The Interaction of Antimalarials with Nucleic Acids

1 reference

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29 October 2018

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1 reference

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29 October 2018

Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells.

1 reference

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29 October 2018

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1 reference

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29 October 2018

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1 reference

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29 October 2018

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1 reference

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29 October 2018

Reaction between DNA and quinacrine and other antimalarials.

1 reference

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29 October 2018

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1 reference

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29 October 2018

Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.

1 reference

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29 October 2018

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1 reference

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29 October 2018

Comparative antitumor activity of ruthenium derivatives with 5'-deoxy-5-fluorouridine in chemically induced colorectal tumors in SD rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

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inferred from PubMed ID database lookup

Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

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inferred from PubMed ID database lookup

Stacking Surface Effect in the DNA Intercalation of Some Polypyridine Platinum(II) Complexes

1 reference

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Cytostatic trans-platinum(II) complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

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Cell Death in Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

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inferred from PubMed ID database lookup

Efficacy of new ruthenium complexes against chemically induced autochthonous colorectal carcinoma in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neither delta- nor lambda-tris(phenanthroline)ruthenium(II) binds to DNA by classical intercalation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

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Antineoplastic activity of three ruthenium derivatives against chemically induced colorectal carcinoma in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20605217

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JINORGBIO.2010.05.002

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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