(Q34023191)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity (English)

1 reference

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13 February 2020

0 references

5

1 reference

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13 February 2020

author name string

Albert C C Lin

1

1 reference

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13 February 2020

Dilan Dissanayake

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Salim Dhanji

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Alisha R Elford

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

12 September 2011

1 reference

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13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

6

1 reference

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13 February 2020

issue

9

1 reference

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13 February 2020

page(s)

e23940

1 reference

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Creative Commons Attribution 4.0 International

13 February 2020

copyright license

start time

12 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

5 July 2018

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Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

5 July 2018

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Development of TLR inhibitors for the treatment of autoimmune diseases

5 July 2018

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Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale

5 July 2018

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Dendritic cells and cytokines in human inflammatory and autoimmune diseases

5 July 2018

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

5 July 2018

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Signaling to NF-kappaB by Toll-like receptors

5 July 2018

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CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

5 July 2018

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Molecular basis for checkpoints in the CD8 T cell response: tolerance versus activation

5 July 2018

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Type I interferon in systemic lupus erythematosus and other autoimmune diseases

5 July 2018

1 reference

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Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

5 July 2018

1 reference

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Signals required for programming effector and memory development by CD8+ T cells

5 July 2018

1 reference

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Dendritic cells in a mature age.

5 July 2018

1 reference

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

5 July 2018

1 reference

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

5 July 2018

1 reference

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IRF-7 is the master regulator of type-I interferon-dependent immune responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Toll-like receptors, endogenous ligands, and systemic autoimmune disease.

5 July 2018

1 reference

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Anti-interleukin-12 antibody for active Crohn's disease

5 July 2018

1 reference

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Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor

5 July 2018

1 reference

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Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice

5 July 2018

1 reference

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Inhibition of STAT4 activation by lisofylline is associated with the protection of autoimmune diabetes

5 July 2018

1 reference

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Interleukin-12 and the regulation of innate resistance and adaptive immunity

5 July 2018

1 reference

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Recognition of pathogen-associated molecular patterns by TLR family

5 July 2018

1 reference

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Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity.

5 July 2018

1 reference

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Regulation of interleukin-12 production in antigen-presenting cells

5 July 2018

1 reference

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Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages.

5 July 2018

1 reference

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Role of antigen-presenting cells in mediating tolerance and autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Role of interleukin-12 in primary influenza virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Mice lacking IL-12 develop polarized Th1 cells during viral infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Functional role of type I and type II interferons in antiviral defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Emergence of virus escape mutants after immunization with epitope vaccine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171407

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Hematopoietic cell-derived interferon controls viral replication and virus-induced disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0023940

Distinct pathways for NF-kappa B regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains

21 January 2018

1 reference

12 December 2020

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

1 reference

12 December 2020

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections

1 reference

12 December 2020

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

12 December 2020

IL-12 is not required for induction of type 1 cytokine responses in viral infections

1 reference

12 December 2020

Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes

1 reference

12 December 2020

Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice

1 reference

12 December 2020

Generation of human dendritic cells that simultaneously secrete IL-12 and have migratory capacity by adenoviral gene transfer of hCD40L in combination with IFN-gamma

1 reference

12 December 2020

Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young no

1 reference

12 December 2020

IL-12 plays a pathologic role at the inflammatory loci in the development of diabetes in NOD mice

1 reference

12 December 2020

Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0023940

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931625%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21931625

1 reference