(Q34025160)

30 July 2017

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title

The role of interleukin-12 and interferon-gamma in GVHD and GVL. (English)

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30 July 2017

Yang YG

1

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30 July 2017

publication date

1 March 2000

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Cytokines, Cellular & Molecular Therapy

30 July 2017

published in

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30 July 2017

volume

6

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30 July 2017

issue

1

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30 July 2017

page(s)

41-46

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Pathophysiologic mechanisms of acute graft-vs.-host disease

30 July 2017

cites work

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Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms

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In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment

21 January 2018

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Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells

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Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice

21 January 2018

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Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets

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New strategies for preventing graft-versus-host disease

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

21 January 2018

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Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors

21 January 2018

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Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

21 January 2018

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21 January 2018

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21 January 2018

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Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.

21 January 2018

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Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Neutralization of interferon-gamma exacerbates pneumocystis-driven interstitial pneumonitis after bone marrow transplantation in mice

21 January 2018

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Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

21 January 2018

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Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines.

21 January 2018

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Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease

21 January 2018

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10.1080/13684730050515903

21 January 2018

Identifiers

DOI

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30 July 2017

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