(Q34028780)

English

Increased tumor oxygenation and drug uptake during anti-angiogenic weekly low dose cyclophosphamide enhances the anti-tumor effect of weekly tirapazamine

scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Increased tumor oxygenation and drug uptake during anti-angiogenic weekly low dose cyclophosphamide enhances the anti-tumor effect of weekly tirapazamine (English)

1 reference

Europe PubMed Central

30 July 2017

angiogenesis inhibitor

1 reference

based on heuristic

inferred from title

author name string

J C Doloff

1

1 reference

Europe PubMed Central

30 July 2017

N Khan

2

1 reference

Europe PubMed Central

30 July 2017

J Ma

3

1 reference

Europe PubMed Central

30 July 2017

E Demidenko

4

1 reference

Europe PubMed Central

30 July 2017

H M Swartz

5

1 reference

Europe PubMed Central

30 July 2017

Y Jounaidi

6

1 reference

Europe PubMed Central

30 July 2017

publication date

1 September 2009

1 reference

Europe PubMed Central

30 July 2017

Current Cancer Drug Targets

1 reference

Europe PubMed Central

30 July 2017

9

1 reference

Europe PubMed Central

30 July 2017

6

1 reference

Europe PubMed Central

30 July 2017

777-788

1 reference

Europe PubMed Central

30 July 2017

Repeated tumor pO(2) measurements by multi-site EPR oximetry as a prognostic marker for enhanced therapeutic efficacy of fractionated radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

5 July 2018

Modulation of the antitumor activity of metronomic cyclophosphamide by the angiogenesis inhibitor axitinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

5 July 2018

Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model

1 reference

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The effects of Efaproxyn (efaproxiral) on subcutaneous RIF-1 tumor oxygenation and enhancement of radiotherapy-mediated inhibition of tumor growth in mice

1 reference

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5 July 2018

Repetitive tissue pO2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

5 July 2018

Low-dose metronomic daily cyclophosphamide and weekly tirapazamine: a well-tolerated combination regimen with enhanced efficacy that exploits tumor hypoxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

1 reference

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Modulation of cytochrome P450 activity: implications for cancer therapy

1 reference

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5 July 2018

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

1 reference

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1 reference

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1 reference

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Effect of VEGF receptor-2 antibody on vascular function and oxygenation in spontaneous and transplanted tumors

1 reference

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1 reference

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The anti-angiogenic basis of metronomic chemotherapy

1 reference

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Manipulating angiogenesis in medicine

1 reference

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1 reference

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Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

1 reference

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1 reference

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Clinical translation of angiogenesis inhibitors

1 reference

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5 July 2018

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

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P450 enzyme expression patterns in the NCI human tumor cell line panel

1 reference

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Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer

1 reference

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5 July 2018

Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy.

1 reference

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5 July 2018

The measurement of oxygen in vivo using EPR techniques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

5 July 2018

Tumor oxygenation: a matter of supply and demand.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

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Lithium phthalocyanine: a probe for electron paramagnetic resonance oximetry in viable biological systems

1 reference

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SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

1 reference

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Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate

1 reference

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A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer

1 reference

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Cancer. Encouraging results for second-generation antiangiogenesis drugs

1 reference

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Effect of RSR13, an allosteric hemoglobin modifier, on oxygenation in murine tumors: an in vivo electron paramagnetic resonance oximetry and bold MRI study.

1 reference

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Two steps forward in the treatment of colorectal cancer

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29 October 2018

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

29 October 2018

Multicellular resistance to tirapazamine is due to restricted extravascular transport: a pharmacokinetic/pharmacodynamic study in HT29 multicellular layer cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

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Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.

1 reference

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1 reference

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Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912211

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

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based on heuristic

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Docetaxel administered on a weekly basis for metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: antitumor activity and correlation with vascular endothelial growth factor levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

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based on heuristic

inferred from PubMed ID database lookup

Phase I and pharmacologic study of paclitaxel administered weekly in patients with relapsed ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologic and cytotoxic effects of tirapazamine in tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19754361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2174/156800909789271503

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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