(Q34030580)

30 July 2017

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title

The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation. (English)

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30 July 2017

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Allan R Brasier

1

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30 July 2017

publication date

3 March 2010

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30 July 2017

published in

Cardiovascular Research

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30 July 2017

volume

86

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30 July 2017

issue

2

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30 July 2017

page(s)

211-218

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An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.

30 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes

5 July 2018

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Lymphotoxin-alpha 1 beta 2 and LIGHT induce classical and noncanonical NF-kappa B-dependent proinflammatory gene expression in vascular endothelial cells

5 July 2018

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Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

5 July 2018

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The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression

5 July 2018

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The role of the adventitia in vascular inflammation

5 July 2018

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Involvement of a novel Rac/RhoA guanosine triphosphatase-nuclear factor-kappaB inducing kinase signaling pathway mediating angiotensin II-induced RelA transactivation.

5 July 2018

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Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo

5 July 2018

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5 July 2018

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5 July 2018

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Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

5 July 2018

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Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice

5 July 2018

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CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells

5 July 2018

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5 July 2018

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

5 July 2018

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Inflammation and cellular immune responses in abdominal aortic aneurysms

5 July 2018

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A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity

5 July 2018

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STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen

5 July 2018

1 reference

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Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

5 July 2018

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Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

5 July 2018

1 reference

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IL-6 transsignaling: the in vivo consequences

5 July 2018

1 reference

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Stat3 dimerization regulated by reversible acetylation of a single lysine residue

5 July 2018

1 reference

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An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.

5 July 2018

1 reference

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Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

5 July 2018

1 reference

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Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.

5 July 2018

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New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27.

5 July 2018

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Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol

5 July 2018

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Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation

5 July 2018

1 reference

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S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells.

5 July 2018

1 reference

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Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

5 July 2018

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Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms

5 July 2018

1 reference

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Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes

5 July 2018

1 reference

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Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

5 July 2018

1 reference

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

5 July 2018

1 reference

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Endothelial dysfunction, hemodynamic forces, and atherogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Rho GTPases and their effector proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

NAD(P)H oxidase: role in cardiovascular biology and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Activators and target genes of Rel/NF-kappaB transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Molecular determinants of NF-kappaB-inducing kinase action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ076

Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ076

TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVQ076

TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912657

IKKgamma /NEMO facilitates the recruitment of the IkappaB proteins into the IkappaB kinase complex

29 October 2018

1 reference

12 December 2020

Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors

1 reference

12 December 2020

Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivo

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12 December 2020

Diabetes-induced activation of canonical and noncanonical nuclear factor-kappaB pathways in renal cortex

1 reference

12 December 2020

RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs

1 reference

12 December 2020

CD40-40L signaling in vascular inflammation

1 reference

12 December 2020

Finally, MALT1 is a protease!

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVQ076

1 reference

30 July 2017

1 reference

30 July 2017

1 reference