(Q34033122)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

HIV accessory proteins: multifunctional components of a complex system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

K Strebel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 January 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

published in

Advances in Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

75-120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB

10 November 2019

cites work

1 reference

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7 January 2021

Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR

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7 January 2021

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

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7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

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7 January 2021

Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells.

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7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages

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7 January 2021

Human immunodeficiency virus type 1 Vif-derived peptides inhibit the viral protease and arrest virus production

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7 January 2021

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.

1 reference

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7 January 2021

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

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7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

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7 January 2021

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

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7 January 2021

Transcomplementation of VIF- HIV-1 mutants in CEM cells suggests that VIF affects late steps of the viral life cycle

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7 January 2021

Human immunodeficiency virus type 1 Vif- mutant particles from restrictive cells: role of Vif in correct particle assembly and infectivity.

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7 January 2021

Diversity of HIV-1 Vpr interactions involves usage of the WXXF motif of host cell proteins

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7 January 2021

Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.

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7 January 2021

The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?

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7 January 2021

The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

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7 January 2021

Lack of effect of cytoplasmic tail truncations on human immunodeficiency virus type 2 ROD env particle release activity.

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7 January 2021

Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.

1 reference

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7 January 2021

Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor

1 reference

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7 January 2021

CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.

1 reference

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7 January 2021

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

HIV-1 nuclear import in search of a leader

1 reference

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7 January 2021

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Prevention of HIV-1 glycoprotein transport by soluble CD4 retained in the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Stimulation of heterologous protein degradation by the Vpu protein of HIV-1 requires the transmembrane and cytoplasmic domains of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Wnt signaling: a common theme in animal development

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The proteolytic cleavage of human immunodeficiency virus type 1 Nef does not correlate with its ability to stimulate virion infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Effects of Vpu expression on Xenopus oocyte membrane conductance

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Identification of a protein encoded by the vpu gene of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cdc2 regulatory factors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Towards a consensus for a role of Nef in both viral replication and immunomodulation?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.

1 reference

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7 January 2021

Evidence for intact CD28 signaling in T cell hyporesponsiveness induced by the HIV-1nef gene

1 reference

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7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The zinc fingers of HIV nucleocapsid protein NCp7 direct interactions with the viral regulatory protein Vpr.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

1 reference

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7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

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7 January 2021

Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Evidence for the association of Nef protein with HIV-2 virions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cell-free transmission of Vif mutants of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Solution structure of the cytoplasmic domain of the human immunodeficiency virus type 1 encoded virus protein U (Vpu).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The sor gene of HIV-1 is required for efficient virus transmission in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Peptides derived from HIV-1 Vif: a non-substrate based novel type of HIV-1 protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV-1 Vpr displays strong anti-apoptotic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Replication of an acutely lethal simian immunodeficiency virus activates and induces proliferation of lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Subcellular localization of the Vif protein of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Role of Vif in human immunodeficiency virus type 1 reverse transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Ion channels formed by HIV-1 Vpu: a modelling and simulation study

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Protein degradation or regulation: Ub the judge

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Role of vif during packing of the core of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Genetic organization of a chimpanzee lentivirus related to HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Interaction and co-encapsidation of human immunodeficiency virus type 1 Gag and Vif recombinant proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

1 reference

7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Selection of the R17Y substitution in SIVmac239 nef coincided with a dramatic increase in plasma viremia and rapid progression to death.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cells surviving infection by human immunodeficiency virus type 1: vif or vpu mutants produce non-infectious or markedly less cytopathic viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type I Nef independently affects virion incorporation of major histocompatibility complex class I molecules and virus infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The Vpr protein of human immunodeficiency virus type 1 binds to nucleocapsid protein p7 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

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7 January 2021

SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase

1 reference

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7 January 2021

Interaction between the Cytoplasmic Domains of HIV-1 Vpu and CD4: Role of Vpu Residues Involved in CD4 Interaction andin VitroCD4 Degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity

1 reference

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7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.

1 reference

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7 January 2021

Simulation of the HIV-1 Vpu transmembrane domain as a pentameric bundle

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages

1 reference

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7 January 2021

The replicative impairment of Vif- mutants of human immunodeficiency virus type 1 correlates with an overall defect in viral DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The ancient regulatory-protein family of WD-repeat proteins

1 reference

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7 January 2021

Erratum: The ancient regulatory-protein family of WD-repeat proteins

1 reference

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7 January 2021

HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells

1 reference

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7 January 2021

Conservation of amino-acid sequence motifs in lentivirus Vif proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Analysis of vif-defective human immunodeficiency virus type 1 (HIV-1) virions synthesized in 'non-permissive' T lymphoid cells stably infected with selectable HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Beta-catenin as oncogene: the smoking gun.

1 reference

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7 January 2021

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Transport routes through the nuclear pore complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Vpr-induced cell cycle arrest is conserved among primate lentiviruses.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The nef gene from a long-term HIV type 1 nonprogressor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Vpu-mediated proteolysis of gp160/CD4 chimeric envelope glycoproteins in the endoplasmic reticulum: requirement of both the anchor and cytoplasmic domains of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

HIV-1 Vpr: G2 cell cycle arrest, macrophages and nuclear transport.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Nef-CD4 physical interaction sensed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The Tyrosine-17 Residue of Nef in SIVsmmPBj14 Is Required for Acute Pathogenesis and Contributes to Replication in Macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Expression of human immunodeficiency virus type 1 vif and vpr mRNAs is rev-dependent and regulated by splicing

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Interaction with the p6 domain of the gag precursor mediates incorporation into virions of Vpr and Vpx proteins from primate lentiviruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Gene acquisition in HIV and SIV

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Evidence for a newly discovered cellular anti-HIV-1 phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Virion incorporation of human immunodeficiency virus type-1 Vif is determined by intracellular expression level and may not be necessary for function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross-species transmission

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Mutational analysis of the human immunodeficiency virus type 1 Vif protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The redox state of cysteines in human immunodeficiency virus type 1 Vif in infected cells and in virions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Simian-human immunodeficiency virus (SHIV) containing the nef/long terminal repeat region of the highly virulent SIVsmmPBj14 causes PBj-like activation of cultured resting peripheral blood mononuclear cells, but the chimera showed No increase in vir

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

A novel gene of HIV-1, vpu, and its 16-kilodalton product

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The HIV 'A' (sor) gene product is essential for virus infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Origin of vpx in lentiviruses

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Complex Evolutionary History of Primate LentiviralvprGenes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Characterization of a leucine-zipper-like domain in Vpr protein of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Cytoplasmic coat proteins involved in endosome function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Phosphorylation of Vif and its role in HIV-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X

7 January 2021

10.1016/S1054-3589(00)48004-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference