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HIV accessory proteins: multifunctional components of a complex system.
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Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
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Europe PubMed Central
title
HIV accessory proteins: multifunctional components of a complex system
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author
Stephan Bour
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
K Strebel
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
publication date
1 January 2000
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Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Advances in Pharmacology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
48
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
75-120
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
cites work
The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB
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Crossref
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7 January 2021
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Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR
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7 January 2021
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Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
1 reference
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Crossref
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7 January 2021
based on heuristic
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Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
1 reference
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Crossref
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7 January 2021
based on heuristic
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Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages
1 reference
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Crossref
reference URL
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7 January 2021
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Human immunodeficiency virus type 1 Vif-derived peptides inhibit the viral protease and arrest virus production
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcomplementation of VIF- HIV-1 mutants in CEM cells suggests that VIF affects late steps of the viral life cycle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
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Human immunodeficiency virus type 1 Vif- mutant particles from restrictive cells: role of Vif in correct particle assembly and infectivity.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
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Diversity of HIV-1 Vpr interactions involves usage of the WXXF motif of host cell proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of effect of cytoplasmic tail truncations on human immunodeficiency virus type 2 ROD env particle release activity.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 nuclear import in search of a leader
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of HIV-1 glycoprotein transport by soluble CD4 retained in the endoplasmic reticulum.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of heterologous protein degradation by the Vpu protein of HIV-1 requires the transmembrane and cytoplasmic domains of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling: a common theme in animal development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The proteolytic cleavage of human immunodeficiency virus type 1 Nef does not correlate with its ability to stimulate virion infectivity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Vpu expression on Xenopus oocyte membrane conductance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a protein encoded by the vpu gene of HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc2 regulatory factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Towards a consensus for a role of Nef in both viral replication and immunomodulation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for intact CD28 signaling in T cell hyporesponsiveness induced by the HIV-1nef gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The zinc fingers of HIV nucleocapsid protein NCp7 direct interactions with the viral regulatory protein Vpr.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a nef allele that causes lymphocyte activation and acute disease in Macaque monkeys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the association of Nef protein with HIV-2 virions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-free transmission of Vif mutants of HIV-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of the cytoplasmic domain of the human immunodeficiency virus type 1 encoded virus protein U (Vpu).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sor gene of HIV-1 is required for efficient virus transmission in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides derived from HIV-1 Vif: a non-substrate based novel type of HIV-1 protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 Vpr displays strong anti-apoptotic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication of an acutely lethal simian immunodeficiency virus activates and induces proliferation of lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subcellular localization of the Vif protein of human immunodeficiency virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Vif in human immunodeficiency virus type 1 reverse transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ion channels formed by HIV-1 Vpu: a modelling and simulation study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myristoylation-dependent binding of HIV-1 Nef to CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein degradation or regulation: Ub the judge
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of vif during packing of the core of HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic organization of a chimpanzee lentivirus related to HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and co-encapsidation of human immunodeficiency virus type 1 Gag and Vif recombinant proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral Protein X
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linking cargo to vesicle formation: receptor tail interactions with coat proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of the R17Y substitution in SIVmac239 nef coincided with a dramatic increase in plasma viremia and rapid progression to death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cells surviving infection by human immunodeficiency virus type 1: vif or vpu mutants produce non-infectious or markedly less cytopathic viruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type I Nef independently affects virion incorporation of major histocompatibility complex class I molecules and virus infectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Vpr protein of human immunodeficiency virus type 1 binds to nucleocapsid protein p7 in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the Cytoplasmic Domains of HIV-1 Vpu and CD4: Role of Vpu Residues Involved in CD4 Interaction andin VitroCD4 Degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simulation of the HIV-1 Vpu transmembrane domain as a pentameric bundle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The replicative impairment of Vif- mutants of human immunodeficiency virus type 1 correlates with an overall defect in viral DNA synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ancient regulatory-protein family of WD-repeat proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erratum: The ancient regulatory-protein family of WD-repeat proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conservation of amino-acid sequence motifs in lentivirus Vif proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of vif-defective human immunodeficiency virus type 1 (HIV-1) virions synthesized in 'non-permissive' T lymphoid cells stably infected with selectable HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin as oncogene: the smoking gun.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transport routes through the nuclear pore complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vpr-induced cell cycle arrest is conserved among primate lentiviruses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral protein R regulates nuclear import of the HIV-1 pre-integration complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nef gene from a long-term HIV type 1 nonprogressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vpu-mediated proteolysis of gp160/CD4 chimeric envelope glycoproteins in the endoplasmic reticulum: requirement of both the anchor and cytoplasmic domains of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Vpr: G2 cell cycle arrest, macrophages and nuclear transport.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nef-CD4 physical interaction sensed with the yeast two-hybrid system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Tyrosine-17 Residue of Nef in SIVsmmPBj14 Is Required for Acute Pathogenesis and Contributes to Replication in Macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of human immunodeficiency virus type 1 vif and vpr mRNAs is rev-dependent and regulated by splicing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction with the p6 domain of the gag precursor mediates incorporation into virions of Vpr and Vpx proteins from primate lentiviruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene acquisition in HIV and SIV
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infection and Pathogenicity of Chimeric Simian‐Human Immunodeficiency Viruses in Macaques: Determinants of High Virus Loads and CD4 Cell Killing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a newly discovered cellular anti-HIV-1 phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virion incorporation of human immunodeficiency virus type-1 Vif is determined by intracellular expression level and may not be necessary for function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross-species transmission
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the human immunodeficiency virus type 1 Vif protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The redox state of cysteines in human immunodeficiency virus type 1 Vif in infected cells and in virions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simian-human immunodeficiency virus (SHIV) containing the nef/long terminal repeat region of the highly virulent SIVsmmPBj14 causes PBj-like activation of cultured resting peripheral blood mononuclear cells, but the chimera showed No increase in vir
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene of HIV-1, vpu, and its 16-kilodalton product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV 'A' (sor) gene product is essential for virus infectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Origin of vpx in lentiviruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex Evolutionary History of Primate LentiviralvprGenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Virion Protein Vpr of Human Immunodeficiency Virus Type 1 with Cellular Transcription Factor Sp1 and trans-Activation of Viral Long Terminal Repeat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a leucine-zipper-like domain in Vpr protein of human immunodeficiency virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoplasmic coat proteins involved in endosome function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Vif and its role in HIV-1 replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2800%2948004-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1054-3589(00)48004-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
10987089
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10987089
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10987089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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