(Q34033785)

English

Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factor

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Aegyptin, a novel mosquito salivary gland protein, specifically binds to collagen and prevents its interaction with platelet glycoprotein VI, integrin alpha2beta1, and von Willebrand factor (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1

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2 January 2020

Fuyuki Tokumasu

2

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2 January 2020

Osvaldo Marinotti

3

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2 January 2020

Jean-Luc Villeval

4

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2 January 2020

José M. Ribeiro

5

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2 January 2020

author name string

Ivo M B Francischetti

6

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2 January 2020

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publication date

24 July 2007

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2 January 2020

Journal of Biological Chemistry

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2 January 2020

282

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2 January 2020

37

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2 January 2020

26928-26938

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

A glycine- and glutamate-rich protein is female salivary gland-specific and abundant in the malaria vector Anopheles dirus B (Diptera: Culicidae).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Thrombus formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

C1qTNF-related protein-1 (CTRP-1): a vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

GPVI and integrin alphaIIb beta3 signaling in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Platelet collagen receptors and coagulation. A characteristic platelet response as possible target for antithrombotic treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Platelet adhesion signalling and the regulation of thrombus formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

An insight into the salivary transcriptome and proteome of the adult female mosquito Culex pipiens quinquefasciatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

The role of collagen in thrombosis and hemostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

The transcriptome of adult female Anopheles darlingi salivary glands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Reciprocal signaling by integrin and nonintegrin receptors during collagen activation of platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Platelet-collagen interaction: is GPVI the central receptor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Platelets in atherothrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Toward a catalog for the transcripts and proteins (sialome) from the salivary gland of the malaria vector Anopheles gambiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Production and characterization of saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion to collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

The extracellular matrix dynamically regulates smooth muscle cell responsiveness to PDGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Collagens and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Anticoagulant repertoire of the hookworm Ancylostoma caninum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

5 July 2018

Reversible binding of nitric oxide by a salivary heme protein from a bloodsucking insect.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Inhibition of hemostasis by a high affinity biogenic amine-binding protein from the saliva of a blood-feeding insect.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Function and evolution of a mosquito salivary protein family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

GP35 ANOAL, an abundant acidic glycoprotein of female Anopheles albimanus saliva

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Adhesion of human and mouse platelets to collagen under shear: a unifying model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Salivary apyrase of Aedes Aegypti: Characterization and secretory fate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

The platelet glycoprotein Ib-von Willebrand factor interaction activates the collagen receptor alpha2beta1 to bind collagen: activation-dependent conformational change of the alpha2-I domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Platelets interact with soluble and insoluble collagens through characteristically different reactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Activation of GPVI by collagen is regulated by alpha2beta1 and secondary mediators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

The glycoprotein VI-phospholipase Cgamma2 signaling pathway controls thrombus formation induced by collagen and tissue factor in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Saratin (an inhibitor of platelet-collagen interaction) decreases platelet aggregation and homocysteine-mediated postcarotid endarterectomy intimal hyperplasia in a dose-dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Cerebrovascular pathology in Alzheimer's disease and leukoaraiosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Development and application of quantum dots for immunocytochemistry of human erythrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

29 October 2018

Platelet-activating-factor-hydrolyzing phospholipase C in the salivary glands and saliva of the mosquito Culex quinquefasciatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

29 October 2018

Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

29 October 2018

Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913440

29 October 2018

COnvulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705669200

21 January 2018

Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effects of saratin on human atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant leech antiplatelet protein specifically blocks platelet deposition on collagen surfaces under flow conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the involvement of the von Willebrand factor-glycoprotein Ib interaction in platelet adhesion to a collagen-coated surface under flow conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet adhesion to native type I collagen fibrils. Role of GPVI in divalent cation-dependent and -independent adhesion and thromboxane A2 generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha(2)beta(1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17650501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M705669200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650501%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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