(Q34035414)

30 July 2017

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title

The molecular basis of growth hormone action (English)

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30 July 2017

Thomas MJ

1

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30 July 2017

publication date

1 February 1998

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Growth Hormone & I G F Research

30 July 2017

published in

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30 July 2017

volume

8

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30 July 2017

issue

1

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30 July 2017

page(s)

3-11

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A hot spot of binding energy in a hormone-receptor interface

1 reference

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7 January 2021

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

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7 January 2021

Binding in the growth hormone receptor complex

1 reference

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7 January 2021

Rational design of potent antagonists to the human growth hormone receptor

1 reference

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7 January 2021

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

1 reference

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7 January 2021

G120R, a human growth hormone antagonist, shows zinc-dependent agonist and antagonist activity on Nb2 cells

1 reference

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7 January 2021

Growth hormone (GH) and a GH antagonist promote GH receptor dimerization and internalization

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Conformational changes required in the human growth hormone receptor for growth hormone signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity

1 reference

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7 January 2021

Cytokine signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The proline-rich region of the GH receptor is essential for JAK2 phosphorylation, activation of cell proliferation, and gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Activation of STAT factors by prolactin, interferon-gamma, growth hormones, and a tyrosine phosphatase inhibitor in rabbit primary mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of Jak2 and Stat proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

1 reference

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7 January 2021

The serum response element can mediate induction of c-fos by growth hormone.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth Hormone Induction of Hepatic Serine Protease Inhibitor 2.1 Transcription Is Mediated by a Stat5-related Factor Binding Synergistically to Two γ-Activated Sites

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A novel growth hormone response element unrelated to STAT (signal transducer and activator of transcription)-binding sites is a bifunctional enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A STAT Factor Mediates the Sexually Dimorphic Regulation of Hepatic Cytochrome P450 3A10/Lithocholic Acid 6β-Hydroxylase Gene Expression by Growth Hormone

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Organization and chromosomal localization of the gene encoding the mouse acid labile subunit of the insulin-like growth factor binding complex

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Rapid changes in gene expression after in vivo growth hormone treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Characterization of orphan nuclear receptor binding elements in sex-differentiated members of the CYP2C gene family expressed in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Interaction of a novel sex-dependent, growth hormone-regulated liver nuclear factor with CYP2C12 promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid- protein interactions within the major promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleic acid-protein interactions within the second promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The regulation by growth hormone of lipoprotein lipase gene expression is mediated by c-fos protooncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone-induced signal tranduction depends on an intact ubiquitin system

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1096-6374%2898%2980316-X

7 January 2021

10.1016/S1096-6374(98)80316-X

Identifiers

DOI

1 reference

30 July 2017

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