(Q34036694)

30 July 2017

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title

Interleukin-6 signal transduction and lymphocyte function (English)

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30 July 2017

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F Horn

1

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30 July 2017

C Henze

series ordinal

2

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30 July 2017

K Heidrich

series ordinal

3

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30 July 2017

publication date

1 August 2000

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30 July 2017

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30 July 2017

volume

202

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30 July 2017

issue

2

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30 July 2017

page(s)

151-167

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Interleukin 6 and its receptor: ten years later

30 July 2017

cites work

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7 January 2021

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

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7 January 2021

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

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7 January 2021

T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor

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7 January 2021

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes

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7 January 2021

Interleukin 6 is essential for in vivo development of B lineage neoplasms

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7 January 2021

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells

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7 January 2021

CD40 ligand triggers interleukin-6 mediated B cell differentiation

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7 January 2021

IL-6 antisense oligonucleotides inhibit IgE production in IL-4 and anti-CD40-stimulated human B-lymphocytes.

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7 January 2021

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

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7 January 2021

Interleukin 6 and plasma cell neoplasias

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7 January 2021

Interleukin-6 inhibits apoptosis of malignant plasma cells

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7 January 2021

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

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7 January 2021

Defective inflammatory response in interleukin 6-deficient mice

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7 January 2021

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

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7 January 2021

Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia

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7 January 2021

Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia

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7 January 2021

Interleukin-6 is required for a protective immune response to systemic Escherichia coli infection

1 reference

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7 January 2021

Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice

1 reference

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7 January 2021

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans

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7 January 2021

IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glucoprotein 35-55 induced experimental autoimmune encephalomyelitis.

1 reference

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7 January 2021

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein

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7 January 2021

Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice

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7 January 2021

Interleukin 6 is required for the development of collagen-induced arthritis

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https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

STATs and gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Growth Hormone Induction of Hepatic Serine Protease Inhibitor 2.1 Transcription Is Mediated by a Stat5-related Factor Binding Synergistically to Two γ-Activated Sites

1 reference

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7 January 2021

Three-dimensional structure of the Stat3beta homodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

1 reference

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7 January 2021

Structure of the amino-terminal protein interaction domain of STAT-4

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Stat3 activation is required for cellular transformation by v-src

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

1 reference

7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Specific inhibition of Stat3 signal transduction by PIAS3

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Inhibition of Stat1-mediated gene activation by PIAS1

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Protein Inhibitor of Activated STAT-1 (Signal Transducer and Activator of Transcription-1) Is a Nuclear Receptor Coregulator Expressed in Human Testis

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Interleukin-6 activates phosphatidylinositol-3 kinase, which inhibits apoptosis in human prostate cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Serine phosphorylation and negative regulation of Stat3 by JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Interleukin-6 dependent induction of the cyclin dependent kinase inhibitor p21WAF1/CIP1 is lost during progression of human malignant melanoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0171-2985%2800%2980061-3

7 January 2021

10.1016/S0171-2985(00)80061-3

Identifiers

DOI

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1 reference