(Q34037250)

30 July 2017

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. (English)

1 reference

30 July 2017

D Sesardic

1

1 reference

30 July 2017

A R Boobis

2

1 reference

30 July 2017

B P Murray

3

1 reference

30 July 2017

S Murray

4

1 reference

30 July 2017

J Segura

5

1 reference

30 July 2017

R de la Torre

6

1 reference

30 July 2017

D S Davies

7

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 June 1990

1 reference

British Journal of Clinical Pharmacology

30 July 2017

1 reference

30 July 2017

29

1 reference

30 July 2017

6

1 reference

30 July 2017

651-663

1 reference

Protein measurement with the Folin phenol reagent

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

The determination of enzyme inhibitor constants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Binding and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene by seven purified forms of cytochrome P-450.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

28 July 2018

Human cytochromes P-450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in man

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Phenacetin O-deethylase: an activity of a cytochrome P-450 showing genetic linkage with that catalysing the 4-hydroxylation of debrisoquine?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Attempts to phenotype human liver samples in vitro for debrisoquine 4-hydroxylase activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Accumulation of caffeine in healthy volunteers treated with furafylline

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Mechanisms of the inhibition of cytochrome P-450-mediated drug oxidation by therapeutic agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Correlation of placental microsomal activities with protein detected by antibodies to rabbit cytochrome P-450 isozyme 6 in preparations from humans exposed to polychlorinated biphenyls, quaterphenyls, and dibenzofurans.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

The molecular biology of cytochrome P450s.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

A simple and sensitive assay of 7-ethoxycoumarin deethylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Drug metabolism in liver disease: Activity of hepatic microsomal metabolizing enzymes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Genetic control of interindividual variations in the inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

In vitro studies of induction and inhibition of drug oxidation in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

Inhibition of rat liver microsomal cytochrome P-450 steroid hydroxylase reactions by imidazole antimycotic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03686.X

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1380167

p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol

29 October 2018

1 reference

12 December 2020

An assay for paracetamol, produced by the O-deethylation of phenacetin in vitro, using gas chromatography/electron capture negative ion chemical ionization mass spectrometry

1 reference

12 December 2020

Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a

1 reference

12 December 2020

Freezing affects the activity and subcellular distribution profile of human placental xenobiotic- and steroid-metabolizing enzymes

1 reference

12 December 2020

Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes

1 reference

12 December 2020

Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies

1 reference

12 December 2020

An animal model for the detection of drug-induced inhibition of caffeine metabolism

1 reference

12 December 2020

Purification of human liver cytochrome P-450 catalyzing testosterone 6 beta-hydroxylation

1 reference

12 December 2020

The effect of cigarette smoking on drug metabolism in the liver and placenta: the use of cotinine in verifying smoking status

1 reference

12 December 2020

On the evaluation of the constants Vm and KM in enzyme reactions

1 reference

12 December 2020

Activation of monooxygenases in human liver by 7,8-benzoflavone

1 reference

12 December 2020

Genetic differences in microsomal electron transport: the Ah locus

1 reference

12 December 2020

A program for non-linear regression analysis to be used on desk-top computers

1 reference

12 December 2020

Cytochrome P-450 monooxygenase activities in human and rat liver microsomes

1 reference

12 December 2020

Effect of heparin on the subcellular distribution of human placental 7-ethoxycoumarin O-deethylase activity

1 reference

12 December 2020

The caffeine CO2 breath test: dose response and route of N-demethylation in smokers and nonsmokers

1 reference

12 December 2020

Effect of cigarette smoking on phenacetin metabolism

1 reference

12 December 2020

Monoclonal antibody-directed radioimmunoassay detects cytochrome P-450 in human placenta and lymphocytes

1 reference

12 December 2020

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

1 reference

12 December 2020

Monoclonal antibodies distinguish among isozymes of the cytochrome P-450b subfamily

1 reference

12 December 2020

10.1111/J.1365-2125.1990.TB03686.X

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference