(Q34038766)

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Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.

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5 March 2020

Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia (English)

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5 March 2020

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5 March 2020

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V El-Khoury

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5 March 2020

S Pierson

2

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5 March 2020

E Szwarcbart

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5 March 2020

N H C Brons

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5 March 2020

O Roland

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5 March 2020

S Cherrier-De Wilde

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5 March 2020

L Plawny

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5 March 2020

E Van Dyck

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5 March 2020

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14 January 2014

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5 March 2020

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5 March 2020

28

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5 March 2020

8

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5 March 2020

1636-1646

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5 March 2020

describes a project that uses

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Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

1 reference

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5 July 2018

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6.

1 reference

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5 July 2018

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape

1 reference

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5 July 2018

Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity

1 reference

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5 July 2018

ER stress and autophagy: new discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol

1 reference

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5 July 2018

Cell-mediated autophagy promotes cancer cell survival.

1 reference

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5 July 2018

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

1 reference

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5 July 2018

p62: a versatile multitasker takes on cancer

1 reference

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5 July 2018

miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

The crosstalk between autophagy and apoptosis: where does this lead?

1 reference

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5 July 2018

Autophagy and cancer

1 reference

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5 July 2018

Interplay between histone deacetylases and autophagy--from cancer therapy to neurodegeneration

1 reference

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5 July 2018

The role of antimalarial agents in the treatment of SLE and lupus nephritis

1 reference

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5 July 2018

Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

1 reference

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5 July 2018

Autophagic and apoptotic effects of HDAC inhibitors on cancer cells

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5 July 2018

Histone deacetylase inhibitor MGCD0103 synergizes with gemcitabine in human pancreatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: potential implications for the treatment of a therapeutic-resistant malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

The in vitro cleavage of the hAtg proteins by cell death proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Regulation of mammalian autophagy in physiology and pathophysiology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Selective degradation of p62 by autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Quality control autophagy: a joint effort of ubiquitin, protein deacetylase and actin cytoskeleton

1 reference

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5 July 2018

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

1 reference

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5 July 2018

Methods in mammalian autophagy research

1 reference

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5 July 2018

From pathogenesis to treatment of chronic lymphocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Control of basal autophagy by calpain1 mediated cleavage of ATG5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131250

5 July 2018

Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease

1 reference

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5 July 2018

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation

1 reference

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Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells?

1 reference

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5 July 2018

Lysine acetylation: codified crosstalk with other posttranslational modifications

1 reference

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Human and murine model cell lines for dendritic cell biology evaluated

1 reference

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Autophagy in the Pathogenesis of Disease

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5 July 2018

Tissue transglutaminase inhibits autophagy in pancreatic cancer cells

1 reference

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Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death

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5 July 2018

Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia

1 reference

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

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Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death

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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

1 reference

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5 July 2018

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

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5 July 2018

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

21 January 2018

The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

21 January 2018

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

21 January 2018

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1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

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1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

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Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.19

21 January 2018

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1 reference

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21 January 2018

p53 and autophagy contribute to dasatinib resistance in primary CLL lymphocytes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24418989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective turnover of p62/A170/SQSTM1 by autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24418989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LEU.2014.19

1 reference

Europe PubMed Central

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5 March 2020

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5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24418989%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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