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The hypothalamus and the regulation of energy homeostasis: lifting the lid on a black box.
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Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
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Europe PubMed Central
title
The hypothalamus and the regulation of energy homeostasis: lifting the lid on a black box
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
G Williams
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
J A Harrold
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
D J Cutler
series ordinal
3
1 reference
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Europe PubMed Central
PubMed ID
10997654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
publication date
1 August 2000
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Europe PubMed Central
PubMed ID
10997654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Proceedings of the Nutrition Society
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
59
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
385-396
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
cites work
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Preprohypocretin (orexin) and prolactin-like immunoreactivity are coexpressed by neurons of the rat lateral hypothalamic area.
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7 January 2021
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Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat
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7 January 2021
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Structure and function of human prepro-orexin gene
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7 January 2021
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7 January 2021
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7 January 2021
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Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin.
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7 January 2021
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Targeted disruption of the melanocortin-4 receptor results in obesity in mice
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7 January 2021
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Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse.
1 reference
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7 January 2021
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Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats.
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7 January 2021
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The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
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Localization of the gene for rapidly progressive autosomal dominant parkinsonism and dementia with pallido-ponto-nigral degeneration to chromosome 17q21
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Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
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7 January 2021
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The role of neuropeptide Y in the antiobesity action of the obese gene product
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7 January 2021
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Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome
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7 January 2021
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Hypothalamic hypocretin/orexin and neuropeptide Y: divergent interaction with energy depletion and leptin.
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Neuropeptide Y innervation of ACTH-immunoreactive neurons in the arcuate nucleus of rats: a correlated light and electron microscopic double immunolabeling study
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Changes in hypothalamic agouti-related protein (AGRP), but not alpha-MSH or pro-opiomelanocortin concentrations in dietary-obese and food-restricted rats.
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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.
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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
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7 January 2021
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Mutations in the carboxyl terminus of the agouti protein decrease agouti inhibition of ligand binding to the melanocortin receptors
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Melanocortin receptors in leptin effects.
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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
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Independent and additive effects of central POMC and leptin pathways on murine obesity.
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7 January 2021
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Cardiovascular regulatory actions of the hypocretins in brain.
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7 January 2021
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Neuropeptide Y and energy balance: one way ahead for the treatment of obesity?
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats.
1 reference
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7 January 2021
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inferred from DOI database lookup
A frameshift mutation in MC4R associated with dominantly inherited human obesity
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of orexin receptor mRNA in the rat brain.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin and the regulation of body weight in mammals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Anatomy and physiology of the neuroendocrine arcuate nucleus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The lateral hypothalamic area revisited: ingestive behavior
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Narcolepsy: a key role for hypocretins (orexins)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
NPY Y1 receptor like immunoreactivity exists in a subpopulation of beta-endorphin immunoreactive nerve cells in the arcuate nucleus: a double immunolabelling analysis in the rat.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of alpha-melanocyte-stimulating hormone release from hypothalamic neurons
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-function analysis of stimulation of food intake by neuropeptide Y: Effects of receptor agonists
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Down regulation of the prepro-orexin gene expression in genetically obese mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution and quantification of immunoreactive orexin A in rat tissues.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for melanin-concentrating hormone in the central regulation of feeding behaviour
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropeptide Y feeding receptors: are multiple subtypes involved?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurons containing hypocretin (orexin) project to multiple neuronal systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationships between hypothalamic neuropeptide Y and food intake in the lactating rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin receptor missense mutation in the fatty Zucker rat.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The emergence of the volume transmission concept1Published on the World Wide Web on 12 January 1998.1
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered neuropeptide Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothalamic orexin expression: modulation by blood glucose and feeding.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Environmental contributions to the obesity epidemic
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Crossref
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https://api.crossref.org/works/10.1017%2FS0029665100000434
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7 January 2021
based on heuristic
inferred from DOI database lookup
Independent feeding and metabolic actions of orexins in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal localisation of neuropeptide Y gene expression in rat brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin enters the brain by a saturable system independent of insulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of orexin neurons in the adult rat brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signals that regulate food intake and energy homeostasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of porcine prepro-orexin cDNA and effects of an intramuscular injection of synthetic porcine orexin-B on feed intake in young pigs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptin receptor- and STAT3-immunoreactivities in hypocretin/orexin neurones of the lateral hypothalamus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Feeding response to central orexins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased neuropeptide Y content in individual hypothalamic nuclei, but not neuropeptide Y mRNA, in diet-induced obesity in rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropeptide Y-related compounds and feeding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0029665100000434
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1017/S0029665100000434
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed ID
10997654
1 reference
stated in
Europe PubMed Central
PubMed ID
10997654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10997654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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