(Q34039622)

30 July 2017

title

The major G-quadruplex formed in the human BCL-2 proximal promoter adopts a parallel structure with a 13-nt loop in K+ solution (English)

1 reference

30 July 2017

Prashansa Agrawal

1

1 reference

30 July 2017

Clement Lin

2

1 reference

30 July 2017

Raveendra I Mathad

3

1 reference

30 July 2017

Megan Carver

4

1 reference

30 July 2017

Danzhou Yang

5

1 reference

30 July 2017

language of work or name

English

0 references

publication date

27 January 2014

1 reference

Journal of the American Chemical Society

30 July 2017

published in

1 reference

30 July 2017

volume

136

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30 July 2017

issue

5

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30 July 2017

page(s)

1750-1753

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Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes

30 July 2017

cites work

1 reference

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c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

5 July 2018

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Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

5 July 2018

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Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop isomers formed in the nuclease hypersensitive element in the human c-Myc promoter: effect of loops and flanking segments on the stability of parallel-stranded intram

5 July 2018

1 reference

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Coexistence of two distinct G-quadruplex conformations in the hTERT promoter

5 July 2018

1 reference

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How long is too long? Effects of loop size on G-quadruplex stability

5 July 2018

1 reference

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Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs.

5 July 2018

1 reference

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A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics

5 July 2018

1 reference

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Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands

5 July 2018

1 reference

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A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes

5 July 2018

1 reference

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Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

5 July 2018

1 reference

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NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Prevalence of quadruplexes in the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Highly prevalent putative quadruplex sequence motifs in human DNA

5 July 2018

1 reference

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

5 July 2018

1 reference

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A phase I trial of a Bcl-2 antisense (G3139) and weekly docetaxel in patients with advanced breast cancer and other solid tumors

5 July 2018

1 reference

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Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment

5 July 2018

1 reference

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Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

The WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas. Aspects of carcinogenesis and prognostic significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

bcl-2 protein in non-small-cell lung carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Expression of Bcl-2 protein and Bcl-2 mRNA in normal and neoplastic lymphoid tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Bcl-2 protein expression and long-term survival in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Anticancer drug resistance and inhibition of apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Regulation of chemoresistance by the bcl-2 oncoprotein in non-Hodgkin's lymphoma and lymphocytic leukemia cell lines

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

The chromosomal basis of human neoplasia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4732354

Causes and consequences of BCL2 overexpression in diffuse large B-cell lymphoma

29 October 2018

1 reference

12 December 2020

The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4

1 reference

12 December 2020

Expression of bcl-2 in invasive and in situ carcinoma of the uterine cervix

1 reference

12 December 2020

Sequence effects of single base loops in intramolecular quadruplex DNA

1 reference

12 December 2020

Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA4118945

1 reference

release_gqozxu6tybebzatom5npclgeam

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gqozxu6tybebzatom5npclgeam

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4732354

1 reference

30 July 2017

1 reference