(Q34042375)

30 July 2017

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title

Genomic circuits and the integrative biology of cardiac diseases (English)

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30 July 2017

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Chien KR

1

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30 July 2017

language of work or name

English

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publication date

1 September 2000

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30 July 2017

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30 July 2017

volume

407

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30 July 2017

issue

6801

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30 July 2017

page(s)

227-232

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Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

30 July 2017

cites work

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7 January 2021

RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice.

1 reference

7 January 2021

A genetic dissection of the retinoid signalling pathway in the mouse

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7 January 2021

Embryonic folate metabolism and mouse neural tube defects

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7 January 2021

WT-1 is required for early kidney development

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7 January 2021

A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region

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7 January 2021

A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects

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7 January 2021

Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice

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7 January 2021

A novel role for cardiac neural crest in heart development

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7 January 2021

Signaling pathways for cardiac hypertrophy and failure

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7 January 2021

Stress pathways and heart failure

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7 January 2021

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

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7 January 2021

Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes

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7 January 2021

Multiple essential functions of neuregulin in development

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7 January 2021

The cellular and molecular response of cardiac myocytes to mechanical stress.

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7 January 2021

Complexity in simplicity: monogenic disorders and complex cardiomyopathies

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7 January 2021

MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

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7 January 2021

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

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7 January 2021

Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene

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7 January 2021

Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene

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7 January 2021

Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease).

1 reference

7 January 2021

Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments

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7 January 2021

Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy

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7 January 2021

Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

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7 January 2021

Molecular regulation of phospholamban function and expression

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7 January 2021

Genes and physiology: molecular physiology in genetically engineered animals

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7 January 2021

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

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7 January 2021

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

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7 January 2021

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

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7 January 2021

Conducting the embryonic heart: orchestrating development of specialized cardiac tissues

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7 January 2021

A novel, tissue-restricted zinc finger protein (HF-1b) binds to the cardiac regulatory element (HF-1b/MEF-2) in the rat myosin light-chain 2 gene

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7 January 2021

A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages

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7 January 2021

Congenital heart disease caused by mutations in the transcription factor NKX2-5

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7 January 2021

Persistent truncus arteriosus in the Splotch mutant mouse

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7 January 2021

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

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7 January 2021

Sox4-deficiency syndrome in mice is an animal model for common trunk.

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7 January 2021

Cardiac malformation in neonatal mice lacking connexin43.

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7 January 2021

Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development

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7 January 2021

Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis

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7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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7 January 2021

Nonmuscle myosin II-B is required for normal development of the mouse heart

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7 January 2021

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

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7 January 2021

Identifiers

DOI

10.1038/35025196

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Dimensions Publication ID

30 July 2017

1010498284

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