(Q34042708)

30 July 2017

title

Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity (English)

1 reference

30 July 2017

Ikhlas S Ahmed

1

1 reference

30 July 2017

Hannah J Rohe

series ordinal

2

1 reference

30 July 2017

Katherine E Twist

series ordinal

3

1 reference

30 July 2017

Rolf J Craven

series ordinal

4

1 reference

30 July 2017

language of work or name

English

0 references

publication date

10 June 2010

1 reference

Journal of Biological Chemistry

30 July 2017

published in

1 reference

30 July 2017

volume

285

1 reference

30 July 2017

issue

32

1 reference

30 July 2017

page(s)

24775-24782

1 reference

Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule

30 July 2017

cites work

1 reference

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Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice

5 July 2018

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Mutations and response to epidermal growth factor receptor inhibitors

5 July 2018

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PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding

5 July 2018

1 reference

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Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1.

5 July 2018

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Survival of cancer cells is maintained by EGFR independent of its kinase activity

5 July 2018

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Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1.

5 July 2018

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Measurement of the heme affinity for yeast dap1p, and its importance in cellular function

5 July 2018

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5 July 2018

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EGFR tyrosine kinase inhibitors in lung cancer: an evolving story

5 July 2018

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Erlotinib in cancer treatment.

5 July 2018

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5 July 2018

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Hypoxia increases the motility of lung adenocarcinoma cell line A549 via activation of the epidermal growth factor receptor pathway

5 July 2018

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Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis

5 July 2018

1 reference

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Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs

5 July 2018

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The complexity of targeting EGFR signalling in cancer: from expression to turnover

5 July 2018

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Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy

5 July 2018

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Spectroscopic and biochemical characterization of heme binding to yeast Dap1p and mouse PGRMC1p

5 July 2018

1 reference

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Molecular identification of adrenal inner zone antigen as a heme-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Hpr6 (heme-1 domain protein) regulates the susceptibility of cancer cells to chemotherapeutic drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

A novel group of genes regulates susceptibility to antineoplastic drugs in highly tumorigenic breast cancer cells

5 July 2018

1 reference

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Silencing the epidermal growth factor receptor gene with RNAi may be developed as a potential therapy for non small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Hpr6.6 protein mediates cell death from oxidative damage in MCF‐7 human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Gene expression profiles in human non-small and small-cell lung cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor

5 July 2018

1 reference

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Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells

5 July 2018

1 reference

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The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Cloning and tissue expression of two putative steroid membrane receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

Epidermal growth factor-related peptides and their receptors in human malignancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915713

PGRMC1: a new biomarker for the estrogen receptor in breast cancer

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Membrane-bound progesterone receptors contain a cytochrome b5-like ligand-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Expression and function of PAIRBP1 within gonadotropin-primed immature rat ovaries: PAIRBP1 regulation of granulosa and luteal cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Caenorhabditis elegans VEM-1, a novel membrane protein, regulates the guidance of ventral nerve cord-associated axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

A simplified method for the preparation of detergent-free lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Progesterone membrane receptor component 1 expression in the immature rat ovary and its role in mediating progesterone's antiapoptotic action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134585

Imaging of human tumor xenografts with an indium-111-labeled anti-epidermal growth factor receptor monoclonal antibody

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20538600

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential sensitivity of A549 non-small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20538600

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.134585

1 reference

30 July 2017

1 reference

30 July 2017

1 reference