(Q34044654)

English

Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Andre Michael Mueller

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Bo Hyung Yoon

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Saud Ahmed Sadiq

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

27 June 2014

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

289

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

33

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

22888-22899

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4132791/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

1 reference

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NIH Image to ImageJ: 25 years of image analysis

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28 July 2018

Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice.

1 reference

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28 July 2018

Hyaluronan as an immune regulator in human diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 July 2018

Hyaluronan Synthesis Mediates the Fibrotic Response of Keratocytes to Transforming Growth Factor β

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 July 2018

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 July 2018

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

1 reference

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28 July 2018

Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 July 2018

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.

1 reference

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28 July 2018

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

1 reference

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28 July 2018

Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition

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Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis

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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

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28 July 2018

The role of hyaluronan degradation products as innate alloimmune agonists.

1 reference

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28 July 2018

Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions

1 reference

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28 July 2018

Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 July 2018

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

1 reference

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28 July 2018

Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Hyaluronan synthesis is required for IL-2-mediated T cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Hyaluronan binding identifies the most proliferative activated and memory T cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Cerebrospinal hepatocyte growth factor levels correlate negatively with disease activity in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.559583

21 January 2018

Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology

1 reference

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21 January 2018

Multiple sclerosis - remyelination failure as a cause of disease progression

1 reference

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28 October 2018

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4132791

28 October 2018

CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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Glucuronidation and sulfation in the rat in vivo. The role of the liver and the intestine in the in vivo clearance of 4-methylumbelliferone

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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inferred from PubMed ID database lookup

Homing of T cells to the central nervous system throughout the course of relapsing experimental autoimmune encephalomyelitis in Thy-1 congenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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based on heuristic

inferred from PubMed ID database lookup

Identification of hyaluronan binding proteins using a biotinylated hyaluronan probe

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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based on heuristic

inferred from PubMed ID database lookup

Hyaluronic-acid-deficient extracellular matrix induced by addition of 4-methylumbelliferone to the medium of cultured human skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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Effect of 4-methylumbelliferone on cell-free synthesis of hyaluronic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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based on heuristic

inferred from PubMed ID database lookup

Requirement for CD44 in activated T cell extravasation into an inflammatory site

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCL12 expression within the CNS contributes to the resistance against experimental autoimmune encephalomyelitis in Albino Oxford rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973214

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inferred from PubMed ID database lookup

Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.559583

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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