(Q34050555)

30 July 2017

title

Inhibition of Ca2+-independent phospholipase A2 results in insufficient insulin secretion and impaired glucose tolerance (English)

1 reference

30 July 2017

1 reference

Keying Song

1

1 reference

30 July 2017

Xu Zhang

2

1 reference

30 July 2017

Chunying Zhao

3

1 reference

30 July 2017

Natasha T Ang

4

1 reference

30 July 2017

Zhongmin Alex Ma

5

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30 July 2017

language of work or name

1 reference

7 October 2004

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30 July 2017

published in

Molecular Endocrinology

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30 July 2017

volume

19

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30 July 2017

issue

2

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30 July 2017

page(s)

504-515

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Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry

30 July 2017

cites work

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5 July 2018

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5 July 2018

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Cloning and expression of a group IV cytosolic Ca2+-dependent phospholipase A2 from rat pancreatic islets. Comparison of the expressed activity with that of an islet group VI cytosolic Ca2+-independent phospholipase A2.

5 July 2018

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5 July 2018

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5 July 2018

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Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin

5 July 2018

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5 July 2018

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5 July 2018

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Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species

5 July 2018

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Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic beta-cells.

5 July 2018

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Amplification of insulin secretion by lipid messengers

5 July 2018

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Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones.

5 July 2018

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Is phospholipase A2 a "glucose sensor" responsible for the phasic pattern of insulin release?

5 July 2018

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Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

5 July 2018

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Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids

5 July 2018

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

5 July 2018

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Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C.

5 July 2018

1 reference

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Pancreatic islet glucose metabolism and regulation of insulin secretion

5 July 2018

1 reference

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Effects of beta-receptor blockade on carbohydrate metabolism

5 July 2018

1 reference

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Inhibition of phospholipase A2 and insulin secretion in pancreatic islets

5 July 2018

1 reference

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Arachidonic acid metabolism in isolated pancreatic islets. VI. Carbohydrate insulin secretagogues must be metabolized to induce eicosanoid release

5 July 2018

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Carbachol stimulation of phospholipase A2 and insulin secretion in pancreatic islets

5 July 2018

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Parallel effects of arachidonic acid on insulin secretion, calmodulin-dependent protein kinase activity and protein kinase C activity in pancreatic islets

5 July 2018

1 reference

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Glucose clamp technique: a method for quantifying insulin secretion and resistance

5 July 2018

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The role of cytosolic phospholipase A(2) in insulin secretion

5 July 2018

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A novel mechanism for the store-operated calcium influx pathway

28 October 2018

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cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells.

28 October 2018

1 reference

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Stimulation of insulin secretion and associated nuclear accumulation of iPLA(2)beta in INS-1 insulinoma cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917620

Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917620

Glucose-induced phosphorylation and activation of a high molecular weight cytosolic phospholipase A2 in neonatal rat pancreatic islets

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917620

Propranolol-induced inhibition of rat brain cytoplasmic phosphatidate phosphohydrolase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917620

A Specific Inhibitor of Cytosolic Phospholipase A2Activity, AACOCF3, Inhibits Glucose-Induced Insulin Secretion from Isolated Rat Islets

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917620

omega-Conotoxin inhibits glucose- and arachidonic acid-induced rises in intracellular [Ca2+] in rat pancreatic islet beta-cells

28 October 2018

1 reference

12 December 2020

Characterization of an ATP-stimulatable Ca(2+)-independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the beta-cell fuel sensor

1 reference

12 December 2020

Arachidonic acid activates the noncapacitative entry of Ca2+ during [Ca2+]i oscillations

1 reference

12 December 2020

Cell-specific Expression and Regulation of a Glucokinase Gene Locus Transgene

1 reference

12 December 2020

Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism

1 reference

12 December 2020

Ca2+-independent phospholipase A2 contributes to the insulinotropic action of cholecystokinin-8 in rat islets: dissociation from the mechanism of carbachol

1 reference

12 December 2020

Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells

1 reference

12 December 2020

Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion

1 reference

12 December 2020

Electrospray ionization/mass spectrometric analyses of human promonocytic U937 cell glycerolipids and evidence that differentiation is associated with membrane lipid composition changes that facilitate phospholipase A2 activation

1 reference

12 December 2020

Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for

1 reference

12 December 2020

Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose

1 reference

12 December 2020

Possible involvement of phospholipase A2 activation and lipoxygenase product(s) in the mechanism of insulin secretion

1 reference

12 December 2020

Studies on the effects of magnesium ion and propranolol on iris muscle phosphatidate phosphohydrolase

1 reference

12 December 2020

Activity of endogenous phospholipase C and phospholipase A2 in glucose stimulated pancreatic islets

1 reference

12 December 2020

Effect of exogenous phospholipase A2 on insulin secretion from perifused rat islets

1 reference

12 December 2020

Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets

1 reference

12 December 2020

Role of phospholipase and calmodulin inhibitors on insulin, arachidonic acid and prostaglandin E2 release

1 reference

12 December 2020

Phasic effects of glucose, phospholipase A2, and lysophospholipids on insulin secretion

1 reference

12 December 2020

Pancreatic islet phospholipase A2: differential, Ca2+-dependent effects of lysophospholipids, arachidonic acid, and its lipoxygenase-derived metabolites on insulin release

1 reference

12 December 2020

Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2

1 reference

12 December 2020

Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion

1 reference

12 December 2020

Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells

1 reference

12 December 2020

Arachidonic acid-induced insulin secretion from rat islets of Langerhans

1 reference

12 December 2020

Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet beta-cells

1 reference

12 December 2020

Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration

1 reference

12 December 2020

The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans

1 reference

12 December 2020

Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet beta-cells and subcellular membranes

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2004-0169

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30 July 2017

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30 July 2017

1 reference