(Q34052044)

English

L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy.

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Christopher Brooks Mobley

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Vincent J. Dalbo

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Carlton D Fox

2

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12 March 2020

Brian S Ferguson

3

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12 March 2020

Rajesh H Amin

4

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12 March 2020

Shawn Baier

6

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12 March 2020

John A Rathmacher

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Jacob M Wilson

8

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Michael D Roberts

9

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12 March 2020

publication date

13 August 2014

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12 March 2020

Journal of the International Society of Sports Nutrition

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

38

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

copyright license

Creative Commons Attribution 4.0 International

15 August 2014

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copyright status

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April 2022 Public Data File from Crossref

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4134516/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy

1 reference

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1 reference

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Inhibition of myostatin signaling through Notch activation following acute resistance exercise

1 reference

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5 July 2018

Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction.

1 reference

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5 July 2018

Measuring protein synthesis with SUnSET: a valid alternative to traditional techniques?

1 reference

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5 July 2018

The role of myostatin in muscle wasting: an overview

1 reference

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5 July 2018

Acute loading and aging effects on myostatin pathway biomarkers in human skeletal muscle after three sequential bouts of resistance exercise

1 reference

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5 July 2018

β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Salmonid genomes have a remarkably expanded akirin family, coexpressed with genes from conserved pathways governing skeletal muscle growth and catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Molecular mechanisms in aging and current strategies to counteract sarcopenia

1 reference

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5 July 2018

Effect of aging on cellular mechanotransduction

1 reference

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5 July 2018

Effects of 28 days of resistance exercise and consuming a commercially available pre-workout supplement, NO-Shotgun(R), on body composition, muscle strength and mass, markers of satellite cell activation, and clinical safety markers in males

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Transcriptional pathways associated with skeletal muscle disuse atrophy in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Creatine enhances differentiation of myogenic C2C12 cells by activating both p38 and Akt/PKB pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Leucine and protein synthesis: mTOR and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Creatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength training

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Myostatin, a negative regulator of muscle mass: implications for muscle degenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by beta-hydroxy-beta-methylbutyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

The molecular basis of skeletal muscle atrophy

1 reference

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5 July 2018

Myostatin negatively regulates satellite cell activation and self-renewal

1 reference

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5 July 2018

Effects of creatine supplementation on performance and training adaptations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Translational control: implications for skeletal muscle hypertrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Myostatin is an inhibitor of myogenic differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Oral creatine supplementation facilitates the rehabilitation of disuse atrophy and alters the expression of muscle myogenic factors in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

5 July 2018

Beta-hydroxy-beta-methylbutyrate (HMB) supplementation and the promotion of muscle growth and strength

1 reference

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1 reference

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5 July 2018

Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training

1 reference

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5 July 2018

Muscle creatine loading in men.

1 reference

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5 July 2018

β-Hydroxy-β-methylbutyrate free acid reduces markers of exercise-induced muscle damage and improves recovery in resistance-trained men.

1 reference

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28 October 2018

Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Myostatin expression during human muscle hypertrophy and subsequent atrophy: increased myostatin with detraining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Akirin1 (Mighty), a novel promyogenic factor regulates muscle regeneration and cell chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Effect of creatine supplementation during cast-induced immobilization on the preservation of muscle mass, strength, and endurance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Effects of resistance exercise with and without creatine supplementation on gene expression and cell signaling in human skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Deleteriuos effects of immobilization upon rat skeletal muscle: role of creatine supplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Effects of oral creatine and resistance training on myogenic regulatory factor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Effects of oral creatine supplementation on muscular strength and body composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4134516

28 October 2018

Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism of myostatin enhances muscle regeneration during sarcopenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mighty is a novel promyogenic factor in skeletal myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of training and creatine supplement on muscle strength and body mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postprandial stimulation of muscle protein synthesis in old rats can be restored by a leucine-supplemented meal

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular hydration state: an important determinant of protein catabolism in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of pre-exercise feeding on serum hormone concentrations and biomarkers of myostatin and ubiquitin proteasome pathway activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25132809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1550-2783-11-38

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132809%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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