Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34054010)
Watch
English
Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
title
Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
main subject
autophagy
0 references
spinal muscular atrophy
1 reference
based on heuristic
inferred from title
author
Elliot J. Androphy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
author name string
Sara K Custer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
language of work or name
English
0 references
publication date
28 June 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
published in
Molecular and Cellular Neuroscience
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
volume
61
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
page(s)
133-140
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4135029/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
The role of autophagy in neurodegenerative disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Neuronal autophagy and neurodegenerative diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
The COPI vesicle complex binds and moves with survival motor neuron within axons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
A reporter cell system to monitor autophagy based on p62/SQSTM1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Cytoprotective roles for autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Early endosomes and endosomal coatomer are required for autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Autophagy in neurite injury and neurodegeneration: in vitro and in vivo models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Protective roles for induction of autophagy in multiple proteinopathies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
Loss of autophagy in the central nervous system causes neurodegeneration in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
A mouse model for spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
The survival motor neuron protein in spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
5 July 2018
In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
28 October 2018
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
28 October 2018
Molecular and phenotypic reassessment of an infrequently used mouse model for spinal muscular atrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
28 October 2018
Degradation of survival motor neuron (SMN) protein is mediated via the ubiquitin/proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
28 October 2018
Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135029
retrieved
28 October 2018
SMN gene deletions in adult-onset spinal muscular atrophy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Aberrant membranes and double-membrane structures accumulate in the axons of Atg5-null Purkinje cells before neuronal death
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Altered macroautophagy in the spinal cord of SOD1 mutant mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Autophagy and autophagic cell death in Dictyostelium
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A new model to study spinal muscular atrophy: Neurite degeneration and cell death is counteracted by BCL-XL Overexpression in motoneurons
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24983518
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MCN.2014.06.006
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PMC publication ID
4135029
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PubMed publication ID
24983518
1 reference
stated in
Europe PubMed Central
PMC publication ID
4135029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24983518%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit